Simon MC - Search Results

1

A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.

Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J, Vallon M, Morton L, Lefai E, Simon MC, Maher JJ, Mithieux G, Rajas F, Annes J, McGuinness OP, Thurston G, Giaccia AJ, Kuo CJ. Wei K, et al. Among authors: simon mc. Nat Med. 2013 Oct;19(10):1331-1337. doi: 10.1038/nm.3295. Epub 2013 Sep 15. Nat Med. 2013. PMID: 24037094 Free PMC article.

2

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC. Maltepe E, et al. Among authors: simon mc. Nature. 1997 Mar 27;386(6623):403-7. doi: 10.1038/386403a0. Nature. 1997. PMID: 9121557

3

An abundant erythroid protein that stabilizes free alpha-haemoglobin.

Kihm AJ, Kong Y, Hong W, Russell JE, Rouda S, Adachi K, Simon MC, Blobel GA, Weiss MJ. Kihm AJ, et al. Among authors: simon mc. Nature. 2002 Jun 13;417(6890):758-63. doi: 10.1038/nature00803. Nature. 2002. PMID: 12066189

4

Regulation of transcription and translation by hypoxia.

Liu L, Simon MC. Liu L, et al. Among authors: simon mc. Cancer Biol Ther. 2004 Jun;3(6):492-7. doi: 10.4161/cbt.3.6.1010. Epub 2004 Jun 8. Cancer Biol Ther. 2004. PMID: 15254394 Review.

5

The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease.

Giaccia AJ, Simon MC, Johnson R. Giaccia AJ, et al. Among authors: simon mc. Genes Dev. 2004 Sep 15;18(18):2183-94. doi: 10.1101/gad.1243304. Genes Dev. 2004. PMID: 15371333 Free PMC article.

6

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation.

Mansfield KD, Guzy RD, Pan Y, Young RM, Cash TP, Schumacker PT, Simon MC. Mansfield KD, et al. Among authors: simon mc. Cell Metab. 2005 Jun;1(6):393-9. doi: 10.1016/j.cmet.2005.05.003. Cell Metab. 2005. PMID: 16054088 Free PMC article.

7

Mxi1 is induced by hypoxia in a HIF-1-dependent manner and protects cells from c-Myc-induced apoptosis.

Corn PG, Ricci MS, Scata KA, Arsham AM, Simon MC, Dicker DT, El-Deiry WS. Corn PG, et al. Among authors: simon mc. Cancer Biol Ther. 2005 Nov;4(11):1285-94. doi: 10.4161/cbt.4.11.2299. Epub 2005 Nov 7. Cancer Biol Ther. 2005. PMID: 16319523

8

Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells.

Hu CJ, Iyer S, Sataur A, Covello KL, Chodosh LA, Simon MC. Hu CJ, et al. Among authors: simon mc. Mol Cell Biol. 2006 May;26(9):3514-26. doi: 10.1128/MCB.26.9.3514-3526.2006. Mol Cell Biol. 2006. PMID: 16611993 Free PMC article.

9

Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro.

Pan Y, Mansfield KD, Bertozzi CC, Rudenko V, Chan DA, Giaccia AJ, Simon MC. Pan Y, et al. Among authors: simon mc. Mol Cell Biol. 2007 Feb;27(3):912-25. doi: 10.1128/MCB.01223-06. Epub 2006 Nov 13. Mol Cell Biol. 2007. PMID: 17101781 Free PMC article.

10

Acute postnatal ablation of Hif-2alpha results in anemia.

Gruber M, Hu CJ, Johnson RS, Brown EJ, Keith B, Simon MC. Gruber M, et al. Among authors: simon mc. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2301-6. doi: 10.1073/pnas.0608382104. Epub 2007 Feb 6. Proc Natl Acad Sci U S A. 2007. PMID: 17284606 Free PMC article.

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