Simoneau A - Search Results

1

Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer.

Vidula N, Dubash T, Lawrence MS, Simoneau A, Niemierko A, Blouch E, Nagy B, Roh W, Chirn B, Reeves BA, Malvarosa G, Lennerz J, Isakoff SJ, Juric D, Micalizzi D, Wander S, Spring L, Moy B, Shannon K, Younger J, Lanman R, Toner M, Iafrate AJ, Getz G, Zou L, Ellisen LW, Maheswaran S, Haber DA, Bardia A. Vidula N, et al. Among authors: simoneau a. Clin Cancer Res. 2020 Sep 15;26(18):4852-4862. doi: 10.1158/1078-0432.CCR-20-0638. Epub 2020 Jun 22. Clin Cancer Res. 2020. PMID: 32571788 Free PMC article.

2

Calcium Influx Guards Replication Forks against Exonuclease 1.

Simoneau A, Zou L. Simoneau A, et al. Mol Cell. 2019 Jun 20;74(6):1103-1105. doi: 10.1016/j.molcel.2019.06.005. Mol Cell. 2019. PMID: 31226273 Free article.

3

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency.

Gupta M, Concepcion CP, Fahey CG, Keshishian H, Bhutkar A, Brainson CF, Sanchez-Rivera FJ, Pessina P, Kim JY, Simoneau A, Paschini M, Beytagh MC, Stanclift CR, Schenone M, Mani DR, Li C, Oh A, Li F, Hu H, Karatza A, Bronson RT, Shaw AT, Hata AN, Wong KK, Zou L, Carr SA, Jacks T, Kim CF. Gupta M, et al. Among authors: simoneau a. Cancer Res. 2020 Sep 15;80(18):3841-3854. doi: 10.1158/0008-5472.CAN-20-1744. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690724 Free PMC article.

4

cGAS suppresses genomic instability as a decelerator of replication forks.

Chen H, Chen H, Zhang J, Wang Y, Simoneau A, Yang H, Levine AS, Zou L, Chen Z, Lan L. Chen H, et al. Among authors: simoneau a. Sci Adv. 2020 Oct 14;6(42):eabb8941. doi: 10.1126/sciadv.abb8941. Print 2020 Oct. Sci Adv. 2020. PMID: 33055160 Free PMC article.

5

An extending ATR-CHK1 circuitry: the replication stress response and beyond.

Simoneau A, Zou L. Simoneau A, et al. Curr Opin Genet Dev. 2021 Dec;71:92-98. doi: 10.1016/j.gde.2021.07.003. Epub 2021 Jul 27. Curr Opin Genet Dev. 2021. PMID: 34329853 Review.

6

The trans cell cycle effects of PARP inhibitors underlie their selectivity toward BRCA1/2-deficient cells.

Simoneau A, Xiong R, Zou L. Simoneau A, et al. Genes Dev. 2021 Sep 1;35(17-18):1271-1289. doi: 10.1101/gad.348479.121. Epub 2021 Aug 12. Genes Dev. 2021. PMID: 34385259 Free PMC article.

7

Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells.

Tirman S, Quinet A, Wood M, Meroni A, Cybulla E, Jackson J, Pegoraro S, Simoneau A, Zou L, Vindigni A. Tirman S, et al. Among authors: simoneau a. Mol Cell. 2021 Oct 7;81(19):4026-4040.e8. doi: 10.1016/j.molcel.2021.09.013. Mol Cell. 2021. PMID: 34624216 Free PMC article.

8

Oncogenic KIT Induces Replication Stress and Confers Cell Cycle Checkpoint Vulnerability in Melanoma.

Njauw CN, Ji Z, Pham DM, Simoneau A, Kumar R, Flaherty KT, Zou L, Tsao H. Njauw CN, et al. Among authors: simoneau a. J Invest Dermatol. 2022 May;142(5):1413-1424.e6. doi: 10.1016/j.jid.2021.07.188. Epub 2021 Oct 21. J Invest Dermatol. 2022. PMID: 34687746 Free article.

9

Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer.

Stanzione M, Zhong J, Wong E, LaSalle TJ, Wise JF, Simoneau A, Myers DT, Phat S, Sade-Feldman M, Lawrence MS, Hadden MK, Zou L, Farago AF, Dyson NJ, Drapkin BJ. Stanzione M, et al. Among authors: simoneau a. Sci Adv. 2022 May 13;8(19):eabn1229. doi: 10.1126/sciadv.abn1229. Epub 2022 May 13. Sci Adv. 2022. PMID: 35559669 Free PMC article.

10

TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.

Yadav T, Zhang JM, Ouyang J, Leung W, Simoneau A, Zou L. Yadav T, et al. Among authors: simoneau a. Mol Cell. 2022 Nov 3;82(21):3985-4000.e4. doi: 10.1016/j.molcel.2022.09.026. Epub 2022 Oct 19. Mol Cell. 2022. PMID: 36265486 Free PMC article.

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