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Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis.
Poisson LM, Suhail H, Singh J, Datta I, Denic A, Labuzek K, Hoda MN, Shankar A, Kumar A, Cerghet M, Elias S, Mohney RP, Rodriguez M, Rattan R, Mangalam AK, Giri S. Poisson LM, et al. Among authors: singh j. J Biol Chem. 2015 Dec 25;290(52):30697-712. doi: 10.1074/jbc.M115.679068. Epub 2015 Nov 6. J Biol Chem. 2015. PMID: 26546682 Free PMC article.
Blood-based untargeted metabolomics in relapsing-remitting multiple sclerosis revealed the testable therapeutic target.
Zahoor I, Suhail H, Datta I, Ahmed ME, Poisson LM, Waters J, Rashid F, Bin R, Singh J, Cerghet M, Kumar A, Hoda MN, Rattan R, Mangalam AK, Giri S. Zahoor I, et al. Among authors: singh j. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2123265119. doi: 10.1073/pnas.2123265119. Epub 2022 Jun 14. Proc Natl Acad Sci U S A. 2022. PMID: 35700359 Free PMC article.
Beneficial Effects of the Direct AMP-Kinase Activator PXL770 in In Vitro and In Vivo Models of X-Linked Adrenoleukodystrophy.
Monternier PA, Parasar P, Theurey P, Gluais Dagorn P, Kaur N, Nagaraja TN, Fouqueray P, Bolze S, Moller DE, Singh J, Hallakou-Bozec S. Monternier PA, et al. Among authors: singh j. J Pharmacol Exp Ther. 2022 Aug;382(2):208-222. doi: 10.1124/jpet.122.001208. Epub 2022 Jun 28. J Pharmacol Exp Ther. 2022. PMID: 35764327 Free PMC article.
8,630 results