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FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells.
Taliaferro-Smith L, Oberlick E, Liu T, McGlothen T, Alcaide T, Tobin R, Donnelly S, Commander R, Kline E, Nagaraju GP, Havel L, Marcus A, Nahta R, O'Regan R. Taliaferro-Smith L, et al. Among authors: donnelly s. Oncotarget. 2015 Mar 10;6(7):4757-72. doi: 10.18632/oncotarget.3023. Oncotarget. 2015. PMID: 25749031 Free PMC article.
Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1.
Sanabria-Figueroa E, Donnelly SM, Foy KC, Buss MC, Castellino RC, Paplomata E, Taliaferro-Smith L, Kaumaya PT, Nahta R. Sanabria-Figueroa E, et al. Among authors: donnelly sm. Mol Pharmacol. 2015 Feb;87(2):150-61. doi: 10.1124/mol.114.095380. Epub 2014 Nov 12. Mol Pharmacol. 2015. PMID: 25391374 Free PMC article.