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Mesenchymal stromal cells primed with Paclitaxel attract and kill leukaemia cells, inhibit angiogenesis and improve survival of leukaemia-bearing mice.
Pessina A, Coccè V, Pascucci L, Bonomi A, Cavicchini L, Sisto F, Ferrari M, Ciusani E, Crovace A, Falchetti ML, Zicari S, Caruso A, Navone S, Marfia G, Benetti A, Ceccarelli P, Parati E, Alessandri G. Pessina A, et al. Among authors: sisto f. Br J Haematol. 2013 Mar;160(6):766-78. doi: 10.1111/bjh.12196. Epub 2013 Jan 7. Br J Haematol. 2013. PMID: 23293837 Free article.
Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery.
Pascucci L, Coccè V, Bonomi A, Ami D, Ceccarelli P, Ciusani E, Viganò L, Locatelli A, Sisto F, Doglia SM, Parati E, Bernardo ME, Muraca M, Alessandri G, Bondiolotti G, Pessina A. Pascucci L, et al. Among authors: sisto f. J Control Release. 2014 Oct 28;192:262-70. doi: 10.1016/j.jconrel.2014.07.042. Epub 2014 Jul 30. J Control Release. 2014. PMID: 25084218
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