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New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
Durcik M, Lovison D, Skok Ž, Durante Cruz C, Tammela P, Tomašič T, Benedetto Tiz D, Draskovits G, Nyerges Á, Pál C, Ilaš J, Peterlin Mašič L, Kikelj D, Zidar N. Durcik M, et al. Among authors: skok z. Eur J Med Chem. 2018 Jun 25;154:117-132. doi: 10.1016/j.ejmech.2018.05.011. Epub 2018 May 10. Eur J Med Chem. 2018. PMID: 29778894 Free PMC article.
An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.
Tiz DB, Skok Ž, Durcik M, Tomašič T, Mašič LP, Ilaš J, Zega A, Draskovits G, Révész T, Nyerges Á, Pál C, Cruz CD, Tammela P, Žigon D, Kikelj D, Zidar N. Tiz DB, et al. Among authors: skok z. Eur J Med Chem. 2019 Apr 1;167:269-290. doi: 10.1016/j.ejmech.2019.02.004. Epub 2019 Feb 10. Eur J Med Chem. 2019. PMID: 30776691
Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity.
Fois B, Skok Ž, Tomašič T, Ilaš J, Zidar N, Zega A, Peterlin Mašič L, Szili P, Draskovits G, Nyerges Á, Pál C, Kikelj D. Fois B, et al. Among authors: skok z. ChemMedChem. 2020 Feb 5;15(3):265-269. doi: 10.1002/cmdc.201900607. Epub 2019 Dec 10. ChemMedChem. 2020. PMID: 31721445
Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors.
Lamut A, Skok Ž, Barančoková M, Gutierrez LJ, Cruz CD, Tammela P, Draskovits G, Szili PÉ, Nyerges Á, Pál C, Molek P, Bratkovič T, Ilaš J, Zidar N, Zega A, Enriz RD, Kikelj D, Tomašič T. Lamut A, et al. Among authors: skok z. Future Med Chem. 2020 Feb;12(4):277-297. doi: 10.4155/fmc-2019-0127. Epub 2020 Feb 11. Future Med Chem. 2020. PMID: 32043377
Rational design of balanced dual-targeting antibiotics with limited resistance.
Nyerges A, Tomašič T, Durcik M, Revesz T, Szili P, Draskovits G, Bogar F, Skok Ž, Zidar N, Ilaš J, Zega A, Kikelj D, Daruka L, Kintses B, Vasarhelyi B, Foldesi I, Kata D, Welin M, Kimbung R, Focht D, Mašič LP, Pal C. Nyerges A, et al. Among authors: skok z. PLoS Biol. 2020 Oct 5;18(10):e3000819. doi: 10.1371/journal.pbio.3000819. eCollection 2020 Oct. PLoS Biol. 2020. PMID: 33017402 Free PMC article.
34 results