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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 5
2000 6
2001 2
2002 5
2003 6
2004 5
2005 10
2006 6
2007 3
2008 8
2009 10
2010 14
2011 5
2012 17
2013 17
2014 14
2015 17
2016 18
2017 24
2018 17
2019 25
2020 23
2021 24
2022 21
2023 17
2024 14

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300 results

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Page 1
The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b.
Bodyak ND, Mosher R, Yurkovetskiy AV, Yin M, Bu C, Conlon PR, Demady DR, DeVit MJ, Gumerov DR, Gurijala VR, Lee W, McGillicuddy D, Park PU, Poling LL, Protopova M, Qin L, Stevenson CA, Ter-Ovanesyan E, Uttard A, Xiao D, Xu J, Xu L, Bergstrom DA, Lowinger TB. Bodyak ND, et al. Mol Cancer Ther. 2021 May;20(5):896-905. doi: 10.1158/1535-7163.MCT-20-0183. Epub 2021 Mar 15. Mol Cancer Ther. 2021. PMID: 33722858
However, this strategy restricts the possible target space. SLC34A2/NaPi2b is a sodium phosphate transporter expressed in a variety of human tumors including lung and ovarian carcinoma, as well as the normal tissues from which these tumors arise. ...
However, this strategy restricts the possible target space. SLC34A2/NaPi2b is a sodium phosphate transporter expressed in a variety o …
SLC34A2 promotes cancer proliferation and cell cycle progression by targeting TMPRSS3 in colorectal cancer.
Yang Y, Wu J, Yu X, Wu Q, Cao H, Dai X, Chen H. Yang Y, et al. Pathol Res Pract. 2022 Jan;229:153706. doi: 10.1016/j.prp.2021.153706. Epub 2021 Nov 24. Pathol Res Pract. 2022. PMID: 34929599
However, the functional mechanism by which SLC34A2 promotes cell growth and cell cycle progression remains poorly understood. Here, we reported that SLC34A2 was overexpressed in CRC by analysis of TCGA and GEO datasets. ...
However, the functional mechanism by which SLC34A2 promotes cell growth and cell cycle progression remains poorly understood. Here, w …
Characterization of SLC34A2 as a Potential Prognostic Marker of Oncological Diseases.
Vlasenkova R, Nurgalieva A, Akberova N, Bogdanov M, Kiyamova R. Vlasenkova R, et al. Biomolecules. 2021 Dec 14;11(12):1878. doi: 10.3390/biom11121878. Biomolecules. 2021. PMID: 34944522 Free PMC article.
It was found that the life expectancy of breast and thymus cancer patients with an SLC34A2 mutation is lower, and it was revealed that SLC34A2 overexpression reduced the life span of patients with brain, ovarian, and pancreatic tumors. Thereby, for these types of on …
It was found that the life expectancy of breast and thymus cancer patients with an SLC34A2 mutation is lower, and it was revealed tha …
New insights in the genetic variant spectrum of SLC34A2 in pulmonary alveolar microlithiasis; a systematic review.
Jönsson ÅLM, Hilberg O, Simonsen U, Christensen JH, Bendstrup E. Jönsson ÅLM, et al. Orphanet J Rare Dis. 2023 May 31;18(1):130. doi: 10.1186/s13023-023-02712-7. Orphanet J Rare Dis. 2023. PMID: 37259144 Free PMC article. Review.
Pulmonary alveolar microlithiasis (PAM) is a rare autosomal recessive lung disease caused by variants in the SLC34A2 gene encoding the sodium-dependent phosphate transport protein 2B, NaPi-2b. ...This systematic review aims to provide an overview of the growing knowledge o …
Pulmonary alveolar microlithiasis (PAM) is a rare autosomal recessive lung disease caused by variants in the SLC34A2 gene encoding th …
Knockdown of SLC34A2 inhibits cell proliferation, metastasis, and elevates chemosensitivity in glioma.
Bao Z, Chen L, Guo S. Bao Z, et al. J Cell Biochem. 2019 Jun;120(6):10205-10214. doi: 10.1002/jcb.28305. Epub 2018 Dec 28. J Cell Biochem. 2019. PMID: 30592329
SLC34A2 has been reported to play critical roles in tumorigenesis and progression. ...To further investigate the roles of SLC34A2 in glioma, lentivirus containing specific SLC34A2 short hairpin RNA (sh-SLC34A2) was used to infect glioma cell lines U251 …
SLC34A2 has been reported to play critical roles in tumorigenesis and progression. ...To further investigate the roles of SLC34A2 …
SLC34A2 Gene mutation of pulmonary alveolar microlithiasis: report of four cases and review of literatures.
Yin X, Wang H, Wu D, Zhao G, Shao J, Dai Y. Yin X, et al. Respir Med. 2013 Feb;107(2):217-22. doi: 10.1016/j.rmed.2012.10.016. Epub 2012 Nov 17. Respir Med. 2013. PMID: 23164546 Free article. Review.
Pulmonary alveolar microlithiasis (PAM) is a rare autosomal recessive disorder characterized by the deposition of calcium phosphate microliths throughout the lungs. Currently the mutation of SLC34A2 gene was considered responsible for PAM. Here we reported the studies on m …
Pulmonary alveolar microlithiasis (PAM) is a rare autosomal recessive disorder characterized by the deposition of calcium phosphate microlit …
The SLC34A2-ROS-HIF-1-induced up-regulation of EZH2 expression promotes proliferation and chemo-resistance to apoptosis in colorectal cancer.
Li X, Xing J, Wang H, Yu E. Li X, et al. Biosci Rep. 2019 May 21;39(5):BSR20180268. doi: 10.1042/BSR20180268. Print 2019 May 31. Biosci Rep. 2019. PMID: 30038060 Free PMC article.
Array analysis displayed that the expression of enhancer of zeste 2 (EZH2) decreased considerably when SLC34A2 was knocked down. We demonstrated that SLC34A2 induced EZH2 expression and activated its promoter activity. ...SLC34A2-ROS-HIF-1-EZH2 signaling path …
Array analysis displayed that the expression of enhancer of zeste 2 (EZH2) decreased considerably when SLC34A2 was knocked down. We d …
SLC34A2 simultaneously promotes papillary thyroid carcinoma growth and invasion through distinct mechanisms.
He J, Zhou M, Li X, Gu S, Cao Y, Xing T, Chen W, Chu C, Gu F, Zhou J, Jin Y, Ma J, Ma D, Zou Q. He J, et al. Oncogene. 2020 Mar;39(13):2658-2675. doi: 10.1038/s41388-020-1181-z. Epub 2020 Jan 31. Oncogene. 2020. PMID: 32005974
Here, we uncovered the functional significance, molecular mechanisms, and clinical impact of solute carrier family 34 member A2 (SLC34A2) in PTC. SLC34A2 was markedly overexpressed in PTC tissues at both mRNA and protein levels compared with matched adjacent normal …
Here, we uncovered the functional significance, molecular mechanisms, and clinical impact of solute carrier family 34 member A2 (SLC34A2 …
Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis.
Jönsson ÅLM, Hernando N, Knöpfel T, Mogensen S, Bendstrup E, Hilberg O, Christensen JH, Simonsen U, Wagner CA. Jönsson ÅLM, et al. Hum Genomics. 2022 Apr 20;16(1):13. doi: 10.1186/s40246-022-00387-y. Hum Genomics. 2022. PMID: 35443721 Free PMC article.
BACKGROUND: Variants in SLC34A2 encoding the sodium-dependent phosphate transport protein 2b (NaPi-IIb) cause the rare lung disease pulmonary alveolar microlithiasis (PAM). ...So far, 30 allelic variants in patients have been reported but only a few have been functionally …
BACKGROUND: Variants in SLC34A2 encoding the sodium-dependent phosphate transport protein 2b (NaPi-IIb) cause the rare lung disease p …
300 results