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Year Number of Results
2005 1
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2007 5
2008 1
2010 1
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2013 2
2014 5
2015 1
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2020 11
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55 results

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Page 1
SLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways.
Ren X, Feng C, Wang Y, Chen P, Wang S, Wang J, Cao H, Li Y, Ji M, Hou P. Ren X, et al. Exp Mol Med. 2023 Aug;55(8):1757-1769. doi: 10.1038/s12276-023-01062-5. Epub 2023 Aug 1. Exp Mol Med. 2023. PMID: 37524874 Free PMC article.
Previous studies have reported that its upregulation promotes breast cancer metastasis by enhancing the influx of zinc ions (Zn(2+)); however, its role in gastric cancer remains totally unclear. Here, we found that SLC39A10 expression was frequently increased in gastric ad …
Previous studies have reported that its upregulation promotes breast cancer metastasis by enhancing the influx of zinc ions (Zn(2+)); howeve …
The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis.
He X, Ge C, Xia J, Xia Z, Zhao L, Huang S, Wang R, Pan J, Cheng T, Xu PF, Wang F, Min J. He X, et al. Adv Sci (Weinh). 2023 Jun;10(17):e2205345. doi: 10.1002/advs.202205345. Epub 2023 Apr 17. Adv Sci (Weinh). 2023. PMID: 37068188 Free PMC article.
The results show that in zebrafish, Slc39a10 is a key regulator of the response to zinc deficiency. Surprisingly, both slc39a10 mutant zebrafish and hematopoietic Slc39a10-deficient mice develop a more severe form of impaired hematopoiesis than animals lackin …
The results show that in zebrafish, Slc39a10 is a key regulator of the response to zinc deficiency. Surprisingly, both slc39a10
SLC39A10 Upregulation Predicts Poor Prognosis, Promotes Proliferation and Migration, and Correlates with Immune Infiltration in Hepatocellular Carcinoma.
Ma Z, Li Z, Wang S, Zhou Q, Ma Z, Liu C, Huang B, Zheng Z, Yang L, Zou Y, Zhang C, Huang S, Hou B. Ma Z, et al. J Hepatocell Carcinoma. 2021 Aug 7;8:899-912. doi: 10.2147/JHC.S320326. eCollection 2021. J Hepatocell Carcinoma. 2021. PMID: 34395329 Free PMC article.
BACKGROUND: Recent evidence has shown that Solute Carrier Family 39 Member 10 (SLC39A10) promoted tumor progression in several cancer types. The study intended to explore the expression and function of SLC39A10 in hepatocellular carcinoma (HCC). METHODS: Multiple bi …
BACKGROUND: Recent evidence has shown that Solute Carrier Family 39 Member 10 (SLC39A10) promoted tumor progression in several cancer …
Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival.
Gao H, Zhao L, Wang H, Xie E, Wang X, Wu Q, Yu Y, He X, Ji H, Rink L, Min J, Wang F. Gao H, et al. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):12940-12945. doi: 10.1073/pnas.1708018114. Epub 2017 Nov 27. Proc Natl Acad Sci U S A. 2017. PMID: 29180421 Free PMC article.
Compared with Slc39a10(fl/fl) mice, Slc39a10(fl/fl);LysM-Cre(+) mice had significantly lower mortality following LPS stimulation as well as reduced liver damage and lower levels of circulating inflammatory cytokines. ...Concomitant knockout of p53 largely rescued th …
Compared with Slc39a10(fl/fl) mice, Slc39a10(fl/fl);LysM-Cre(+) mice had significantly lower mortality following LPS stimulati …
Dual inhibition of MYC and SLC39A10 by a novel natural product STAT3 inhibitor derived from Chaetomium globosum suppresses tumor growth and metastasis in gastric cancer.
Guan X, Yang J, Wang W, Zhao B, Hu S, Yu D, Yuan L, Shi Y, Xu J, Dong J, Wang J, Cheng XD, Qin JJ. Guan X, et al. Pharmacol Res. 2023 Mar;189:106703. doi: 10.1016/j.phrs.2023.106703. Epub 2023 Feb 17. Pharmacol Res. 2023. PMID: 36804016 Free article.
The molecular mechanism studies based on transcriptomics and proteomics analyses indicated that XYA-2 might exert its anticancer activity by synergistically inhibiting the expression of MYC and SLC39A10, two downstream genes of STAT3 in vitro and in vivo. Together, these f …
The molecular mechanism studies based on transcriptomics and proteomics analyses indicated that XYA-2 might exert its anticancer activity by …
Bioinformatic analysis reveals an exosomal miRNA-mRNA network in colorectal cancer.
Ma J, Wang P, Huang L, Qiao J, Li J. Ma J, et al. BMC Med Genomics. 2021 Feb 27;14(1):60. doi: 10.1186/s12920-021-00905-2. BMC Med Genomics. 2021. PMID: 33639954 Free PMC article.
The exosomal miRNA-mRNA network with high connectivity contained 13 hub mRNAs (CBFB, CDH3, ETV4, FOXQ1, FUT1, GCNT2, GRIN2D, KIAA1549, KRT80, LZTS1, SLC39A10, SPTBN2, and ZSWIM4) and five hub exosomal miRNAs (hsa-miR-126, hsa-miR-139, hsa-miR-141, hsa-miR-29c, and hsa-miR- …
The exosomal miRNA-mRNA network with high connectivity contained 13 hub mRNAs (CBFB, CDH3, ETV4, FOXQ1, FUT1, GCNT2, GRIN2D, KIAA1549, KRT80 …
LncRNA MCM3AP-AS1 Promotes Cell Proliferation and Invasion Through Regulating miR-543-3p/SLC39A10/PTEN Axis in Prostate Cancer.
Jia Z, Li W, Bian P, Liu H, Pan D, Dou Z. Jia Z, et al. Onco Targets Ther. 2020 Sep 22;13:9365-9376. doi: 10.2147/OTT.S245537. eCollection 2020. Onco Targets Ther. 2020. PMID: 33061424 Free PMC article. Retracted.
Bioinformatics analysis and Luciferase assay were used to explore the relationship between lncRNA MCM3AP-AS1, miR-543-3p and SLC39A10. RESULTS: In PCa tissue samples and cell lines, lncRNA MCM3AP-AS1 was up-regulated while miR-543-3p was down-regulated. ...We further verif …
Bioinformatics analysis and Luciferase assay were used to explore the relationship between lncRNA MCM3AP-AS1, miR-543-3p and SLC39A10
Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength.
Hojyo S, Miyai T, Fujishiro H, Kawamura M, Yasuda T, Hijikata A, Bin BH, Irié T, Tanaka J, Atsumi T, Murakami M, Nakayama M, Ohara O, Himeno S, Yoshida H, Koseki H, Ikawa T, Mishima K, Fukada T. Hojyo S, et al. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11786-91. doi: 10.1073/pnas.1323557111. Epub 2014 Jul 29. Proc Natl Acad Sci U S A. 2014. PMID: 25074919 Free PMC article.
However, the molecular mechanisms underlying this Zn-mediated modulation are largely unknown. Here, we show that the Zn transporter SLC39A10/ZIP10 plays an important role in B-cell antigen receptor (BCR) signal transduction. ...
However, the molecular mechanisms underlying this Zn-mediated modulation are largely unknown. Here, we show that the Zn transporter SLC39
55 results