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Year Number of Results
2004 1
2005 1
2006 1
2007 2
2009 3
2010 1
2011 7
2012 6
2013 3
2014 9
2015 5
2016 6
2017 10
2018 5
2019 7
2020 8
2021 16
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2023 22
2024 9

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122 results

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Page 1
SLC8A1 antisense RNA 1 suppresses papillary thyroid cancer malignant progression via the FUS RNA binding protein (FUS)/NUMB like endocytic adaptor protein (Numbl) axis.
Xin Y, Shang X, Sun X, Xu G, Liu Y, Liu Y. Xin Y, et al. Bioengineered. 2022 May;13(5):12572-12582. doi: 10.1080/21655979.2022.2073125. Bioengineered. 2022. PMID: 35599603 Free PMC article.
This study aimed to explore the role of long non-coding RNA (lncRNA) SLC8A1 antisense RNA 1 (SLC8A1-AS1) in the pathogenesis of PTC. In this study, we explored the function of SLC8A1-AS1 in PTC progression. ...SLC8A1-AS1 and FUS may be potential target …
This study aimed to explore the role of long non-coding RNA (lncRNA) SLC8A1 antisense RNA 1 (SLC8A1-AS1) in the pathogenesis o …
LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.
Proteau S, Krossa I, Husser C, Guéguinou M, Sella F, Bille K, Irondelle M, Dalmasso M, Barouillet T, Cheli Y, Pisibon C, Arrighi N, Nahon-Estève S, Martel A, Gastaud L, Lassalle S, Mignen O, Brest P, Mazure NM, Bost F, Baillif S, Landreville S, Turcotte S, Hasson D, Carcamo S, Vandier C, Bernstein E, Yvan-Charvet L, Levesque MP, Ballotti R, Bertolotto C, Strub T. Proteau S, et al. EMBO Mol Med. 2023 Dec 7;15(12):e17719. doi: 10.15252/emmm.202317719. Epub 2023 Nov 15. EMBO Mol Med. 2023. PMID: 37966164 Free PMC article.
Functionally, LKB1 loss enhances proliferation and survival through SIK2 inhibition and upregulation of the sodium/calcium (Na(+) /Ca(2+) ) exchanger SLC8A1. This signaling cascade promotes increased levels of intracellular calcium and mitochondrial reactive oxygen species …
Functionally, LKB1 loss enhances proliferation and survival through SIK2 inhibition and upregulation of the sodium/calcium (Na(+) /Ca(2+) ) …
Circ-SLC8A1 regulates osteoporosis through blocking the inhibitory effect of miR-516b-5p on AKAP2 expression.
Lin C, Zhong W, Yan W, Yang J, Zheng W, Wu Q. Lin C, et al. J Gene Med. 2020 Nov;22(11):e3263. doi: 10.1002/jgm.3263. Epub 2020 Sep 9. J Gene Med. 2020. PMID: 32830397
RESULTS: The first six circRNAs captured from the 30 circRNAs with highest expression in the bone marrow were examined in a mouse model of osteoporosis and the expression of circ-SLC8A1 was found to be significantly reduced in osteoporosis. Circ-SLC8A1 negatively re …
RESULTS: The first six circRNAs captured from the 30 circRNAs with highest expression in the bone marrow were examined in a mouse model of o …
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C. Huang T, et al. Autophagy. 2021 Nov;17(11):3592-3606. doi: 10.1080/15548627.2021.1885203. Epub 2021 Feb 25. Autophagy. 2021. PMID: 33629929 Free PMC article.
Given the low toxicity and high tolerability of CBD, we therefore propose CBD should be tested clinically for glioma, both alone and in combination with temozolomide.Abbreviations: 4-PBA: 4-phenylbutyrate; AKT: AKT serine/threonine kinase; ATF4: activating transcription factor 4; …
Given the low toxicity and high tolerability of CBD, we therefore propose CBD should be tested clinically for glioma, both alone and in comb …
Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy.
Marchiano S, Nakamura K, Reinecke H, Neidig L, Lai M, Kadota S, Perbellini F, Yang X, Klaiman JM, Blakely LP, Karbassi E, Fields PA, Fenix AM, Beussman KM, Jayabalu A, Kalucki FA, Potter JC, Futakuchi-Tsuchida A, Weber GJ, Dupras S, Tsuchida H, Pabon L, Wang L, Knollmann BC, Kattman S, Thies RS, Sniadecki N, MacLellan WR, Bertero A, Murry CE. Marchiano S, et al. Cell Stem Cell. 2023 Apr 6;30(4):396-414.e9. doi: 10.1016/j.stem.2023.03.010. Cell Stem Cell. 2023. PMID: 37028405 Free PMC article.
Abolishing depolarization-associated genes HCN4, CACNA1H, and SLC8A1, along with overexpressing hyperpolarization-associated KCNJ2, creates hPSC-CMs that lack automaticity but contract when externally stimulated. ...
Abolishing depolarization-associated genes HCN4, CACNA1H, and SLC8A1, along with overexpressing hyperpolarization-associated KCNJ2, c …
A novel SLC8A1-ALK fusion in lung adenocarcinoma confers sensitivity to alectinib: A case report.
Deng L, Tian P, Qiu Z, Wang K, Li Y. Deng L, et al. Open Life Sci. 2022 Aug 11;17(1):846-850. doi: 10.1515/biol-2022-0090. eCollection 2022. Open Life Sci. 2022. PMID: 36045716 Free PMC article.
ALK rearrangements often occur at a common breakpoint in exon 20 of the genome. SLC8A1-ALK, a novel fusion protein partner, comes from exon 2 of the SLC8A1 gene rearranged with exon 20 of the ALK gene. Here, we reported a patient with advanced lung adenocarcinoma ha …
ALK rearrangements often occur at a common breakpoint in exon 20 of the genome. SLC8A1-ALK, a novel fusion protein partner, comes fro …
Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis.
Wang X, Song J, Yuan Y, Li L, Abu-Taha I, Heijman J, Sun L, Dobrev S, Kamler M, Xie L, Wehrens XHT, Horrigan FT, Dobrev D, Li N. Wang X, et al. Circ Res. 2023 Jun 23;133(1):e1-e16. doi: 10.1161/CIRCRESAHA.122.322213. Epub 2023 May 8. Circ Res. 2023. PMID: 37154033 Free article.
Enhanced AF susceptibility in cardiomyocyte-specific knockdown mice was associated with the development of action potential alternans and spontaneous Ca(2+) waves, and increased protein levels and activity of the NCX1 (Na(+)/Ca(2+)-exchanger 1), mimicking the cellular phenotype o …
Enhanced AF susceptibility in cardiomyocyte-specific knockdown mice was associated with the development of action potential alternans and sp …
circRNA_SLC8A1 promotes the survival of mycobacterium tuberculosis in macrophages by upregulating expression of autophagy-related protein SQSTM1/p62 to activate the NF-kappaB pathway.
Li Z, Gao Y, Zhang B, Dong W, Xi Y, Li Y, Cui J. Li Z, et al. Sci Rep. 2024 Mar 4;14(1):5233. doi: 10.1038/s41598-024-55493-9. Sci Rep. 2024. PMID: 38433218 Free PMC article.
Therefore, this study aimed to investigate the role of circRNA_SLC8A1 in the anti-tuberculosis activity of macrophages. We showed that circRNA_SLC8A1 was upregulated in tuberculosis patients. ...Next, we found that miR-20b-5p expression was decreased, while SQSTM1 p …
Therefore, this study aimed to investigate the role of circRNA_SLC8A1 in the anti-tuberculosis activity of macrophages. We showed tha …
Circular RNA SLC8A1 triggers hippocampal neuronal ferroptosis by regulating FUS-mediated ATF3 mRNA stability in epilepsy.
Kang Q, Zhang J, Xie C, Fang S, Chai W. Kang Q, et al. Exp Cell Res. 2024 Jan 1;434(1):113848. doi: 10.1016/j.yexcr.2023.113848. Epub 2023 Oct 31. Exp Cell Res. 2024. PMID: 37918704
Ferroptosis, a recently defined iron-dependent regulated cell death, has been suggested as a potential therapeutic target for epilepsy due to its association with oxidative stress. Additionally, circRNA SLC8A1 (circSLC8A1) has been implicated in various neurological disord …
Ferroptosis, a recently defined iron-dependent regulated cell death, has been suggested as a potential therapeutic target for epilepsy due t …
Abnormal expression and role of MicroRNA-214-3p/SLC8A1 in neonatal Hypoxic-Ischaemic encephalopathy.
Yang L, Zhang L, Zhu J, Wang Y, Zou N, Liu Z, Wang Y. Yang L, et al. Int J Exp Pathol. 2023 Aug;104(4):199-208. doi: 10.1111/iep.12475. Epub 2023 Apr 9. Int J Exp Pathol. 2023. PMID: 37032493 Free PMC article.
The expression of miR-214-3p was significantly down-regulated, while that of Slc8a1, a direct target of miR-214-3p, was significantly up-regulated, in the brain tissue of neonatal HIE rats. ...
The expression of miR-214-3p was significantly down-regulated, while that of Slc8a1, a direct target of miR-214-3p, was significantly …
122 results