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Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.
Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM. Koves TR, et al. Among authors: slentz d. J Biol Chem. 2005 Sep 30;280(39):33588-98. doi: 10.1074/jbc.M507621200. Epub 2005 Aug 3. J Biol Chem. 2005. PMID: 16079133 Free article.
Obesity and lipid stress inhibit carnitine acetyltransferase activity.
Seiler SE, Martin OJ, Noland RC, Slentz DH, DeBalsi KL, Ilkayeva OR, An J, Newgard CB, Koves TR, Muoio DM. Seiler SE, et al. J Lipid Res. 2014 Apr;55(4):635-44. doi: 10.1194/jlr.M043448. Epub 2014 Jan 6. J Lipid Res. 2014. PMID: 24395925 Free PMC article.
Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle.
DeBalsi KL, Wong KE, Koves TR, Slentz DH, Seiler SE, Wittmann AH, Ilkayeva OR, Stevens RD, Perry CG, Lark DS, Hui ST, Szweda L, Neufer PD, Muoio DM. DeBalsi KL, et al. Among authors: slentz dh. J Biol Chem. 2014 Mar 21;289(12):8106-20. doi: 10.1074/jbc.M113.511535. Epub 2014 Jan 30. J Biol Chem. 2014. PMID: 24482226 Free PMC article.
Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis.
Kraus WE, Muoio DM, Stevens R, Craig D, Bain JR, Grass E, Haynes C, Kwee L, Qin X, Slentz DH, Krupp D, Muehlbauer M, Hauser ER, Gregory SG, Newgard CB, Shah SH. Kraus WE, et al. Among authors: slentz dh. PLoS Genet. 2015 Nov 5;11(11):e1005553. doi: 10.1371/journal.pgen.1005553. eCollection 2015 Nov. PLoS Genet. 2015. PMID: 26540294 Free PMC article.
Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.
Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM. Fisher-Wellman KH, et al. Among authors: slentz dh. Cell Rep. 2019 Feb 5;26(6):1557-1572.e8. doi: 10.1016/j.celrep.2019.01.057. Cell Rep. 2019. PMID: 30726738 Free PMC article.
Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction.
Williams AS, Koves TR, Davidson MT, Crown SB, Fisher-Wellman KH, Torres MJ, Draper JA, Narowski TM, Slentz DH, Lantier L, Wasserman DH, Grimsrud PA, Muoio DM. Williams AS, et al. Among authors: slentz dh. Cell Metab. 2020 Jan 7;31(1):131-147.e11. doi: 10.1016/j.cmet.2019.11.003. Epub 2019 Dec 5. Cell Metab. 2020. PMID: 31813822 Free PMC article.
33 results