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Clinical immunogenicity of the d-amino acid peptide therapeutic etelcalcetide: Method development challenges and anti-drug antibody clinical impact assessments.
J Immunol Methods. 2017 Jun;445:37-44. doi: 10.1016/j.jim.2017.03.005. Epub 2017 Mar 6.
J Immunol Methods. 2017.
PMID: 28274835
Clinical Trial.
Pharmacokinetics, Biotransformation, and Excretion of [14C]Etelcalcetide (AMG 416) Following a Single Microtracer Intravenous Dose in Patients with Chronic Kidney Disease on Hemodialysis.
Subramanian R, Zhu X, Hock MB, Sloey BJ, Wu B, Wilson SF, Egbuna O, Slatter JG, Xiao J, Skiles GL.
Subramanian R, et al. Among authors: sloey bj.
Clin Pharmacokinet. 2017 Feb;56(2):179-192. doi: 10.1007/s40262-016-0433-0.
Clin Pharmacokinet. 2017.
PMID: 27517676
Free PMC article.
Clinical Trial.
Item in Clipboard
Experimental and statistical approaches in method cross-validation to support pharmacokinetic decisions.
Thway TM, Ma M, Lee J, Sloey B, Yu S, Wang YM, Desilva B, Graves T.
Thway TM, et al. Among authors: sloey b.
J Pharm Biomed Anal. 2009 Apr 5;49(3):613-8. doi: 10.1016/j.jpba.2008.12.008. Epub 2008 Dec 13.
J Pharm Biomed Anal. 2009.
PMID: 19150189
Item in Clipboard
Investigation of the pharmacokinetics of romiplostim in rodents with a focus on the clearance mechanism.
Wang YM, Sloey B, Wong T, Khandelwal P, Melara R, Sun YN.
Wang YM, et al. Among authors: sloey b.
Pharm Res. 2011 Aug;28(8):1931-8. doi: 10.1007/s11095-011-0420-y. Epub 2011 Apr 8.
Pharm Res. 2011.
PMID: 21476045
Item in Clipboard
Pharmacokinetic and pharmacodynamic modeling of romiplostim in animals.
Krzyzanski W, Sutjandra L, Perez-Ruixo JJ, Sloey B, Chow AT, Wang YM.
Krzyzanski W, et al. Among authors: sloey b.
Pharm Res. 2013 Mar;30(3):655-69. doi: 10.1007/s11095-012-0894-2. Epub 2012 Dec 19.
Pharm Res. 2013.
PMID: 23250851
Item in Clipboard
Dose-related differences in the pharmacodynamic and toxicologic response to a novel hyperglycosylated analog of recombinant human erythropoietin in Sprague-Dawley rats with similarly high hematocrit.
Andrews DA, Boren BM, Turk JR, Boyce RW, He YD, Hamadeh HK, Mytych DT, Barger TE, Salimi-Moosavi H, Sloey B, Elliott S, McElroy P, Sinclair AM, Shimamoto G, Pyrah IT, Lightfoot-Dunn RM.
Andrews DA, et al. Among authors: sloey b.
Toxicol Pathol. 2014;42(3):524-39. doi: 10.1177/0192623313486319. Epub 2013 May 14.
Toxicol Pathol. 2014.
PMID: 23674391
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Cytokines associated with increased erythropoiesis in Sprague-Dawley rats administered a novel hyperglycosylated analog of recombinant human erythropoietin.
Andrews DA, Hamadeh HK, He YD, Boren BM, Turk JR, Boyce RW, Mytych DT, Barger TE, Salimi-Moosavi H, Sloey B, Elliott S, McElroy P, Sinclair AM, Shimamoto G, Pyrah IT, Lightfoot-Dunn RM.
Andrews DA, et al. Among authors: sloey b.
Toxicol Pathol. 2014;42(3):540-54. doi: 10.1177/0192623313486318. Epub 2013 May 14.
Toxicol Pathol. 2014.
PMID: 23674392
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