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Page 1
Preclinical modeling of myelodysplastic syndromes.
Rouault-Pierre K, Mian SA, Goulard M, Abarrategi A, Di Tulio A, Smith AE, Mohamedali A, Best S, Nloga AM, Kulasekararaj AG, Ades L, Chomienne C, Fenaux P, Dosquet C, Mufti GJ, Bonnet D. Rouault-Pierre K, et al. Among authors: smith ae. Leukemia. 2017 Dec;31(12):2702-2708. doi: 10.1038/leu.2017.172. Epub 2017 Jun 2. Leukemia. 2017. PMID: 28663577 Free PMC article.
TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis.
Kulasekararaj AG, Smith AE, Mian SA, Mohamedali AM, Krishnamurthy P, Lea NC, Gäken J, Pennaneach C, Ireland R, Czepulkowski B, Pomplun S, Marsh JC, Mufti GJ. Kulasekararaj AG, et al. Among authors: smith ae. Br J Haematol. 2013 Mar;160(5):660-72. doi: 10.1111/bjh.12203. Epub 2013 Jan 9. Br J Haematol. 2013. PMID: 23297687 Free article.
Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies.
Gaymes TJ, Mohamedali AM, Patterson M, Matto N, Smith A, Kulasekararaj A, Chelliah R, Curtin N, Farzaneh F, Shall S, Mufti GJ. Gaymes TJ, et al. Among authors: smith a. Haematologica. 2013 Sep;98(9):1397-406. doi: 10.3324/haematol.2012.079251. Epub 2013 Jan 24. Haematologica. 2013. PMID: 23349304 Free PMC article.
Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome.
Mohamedali AM, Smith AE, Gaken J, Lea NC, Mian SA, Westwood NB, Strupp C, Gattermann N, Germing U, Mufti GJ. Mohamedali AM, et al. Among authors: smith ae. J Clin Oncol. 2009 Aug 20;27(24):4002-6. doi: 10.1200/JCO.2009.22.6985. Epub 2009 Jun 15. J Clin Oncol. 2009. PMID: 19528370
A functional assay for microRNA target identification and validation.
Gäken J, Mohamedali AM, Jiang J, Malik F, Stangl D, Smith AE, Chronis C, Kulasekararaj AG, Thomas NS, Farzaneh F, Tavassoli M, Mufti GJ. Gäken J, et al. Nucleic Acids Res. 2012 May;40(10):e75. doi: 10.1093/nar/gks145. Epub 2012 Feb 9. Nucleic Acids Res. 2012. PMID: 22323518 Free PMC article.
Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value.
Smith AE, Mohamedali AM, Kulasekararaj A, Lim Z, Gäken J, Lea NC, Przychodzen B, Mian SA, Nasser EE, Shooter C, Westwood NB, Strupp C, Gattermann N, Maciejewski JP, Germing U, Mufti GJ. Smith AE, et al. Blood. 2010 Nov 11;116(19):3923-32. doi: 10.1182/blood-2010-03-274704. Epub 2010 Aug 6. Blood. 2010. PMID: 20693430 Free article.
Functional characterization of CD4+ T cells in aplastic anemia.
Kordasti S, Marsh J, Al-Khan S, Jiang J, Smith A, Mohamedali A, Abellan PP, Veen C, Costantini B, Kulasekararaj AG, Benson-Quarm N, Seidl T, Mian SA, Farzaneh F, Mufti GJ. Kordasti S, et al. Among authors: smith a. Blood. 2012 Mar 1;119(9):2033-43. doi: 10.1182/blood-2011-08-368308. Epub 2011 Dec 2. Blood. 2012. PMID: 22138514 Free article.
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