Smith JD - Search Results

1

Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at sigma-receptors.

Glennon RA, Ismaiel AM, Smith JD, Yousif M, el-Ashmawy M, Herndon JL, Fischer JB, Howie KJ, Server AC. Glennon RA, et al. Among authors: smith jd. J Med Chem. 1991 Jun;34(6):1855-9. doi: 10.1021/jm00110a015. J Med Chem. 1991. PMID: 1648139

2

Identification and exploitation of the sigma-opiate pharmacophore.

Glennon RA, Smith JD, Ismaiel AM, el-Ashmawy M, Battaglia G, Fischer JB. Glennon RA, et al. Among authors: smith jd. J Med Chem. 1991 Mar;34(3):1094-8. doi: 10.1021/jm00107a033. J Med Chem. 1991. PMID: 1848295

3

(-)PPAP: a new and selective ligand for sigma binding sites.

Glennon RA, Battaglia G, Smith JD. Glennon RA, et al. Among authors: smith jd. Pharmacol Biochem Behav. 1990 Nov;37(3):557-9. doi: 10.1016/0091-3057(90)90027-f. Pharmacol Biochem Behav. 1990. PMID: 1965044

4

N-(phthalimidoalkyl) derivatives of serotonergic agents: a common interaction at 5-HT1A serotonin binding sites?

Glennon RA, Naiman NA, Pierson ME, Smith JD, Ismaiel AM, Titeler M, Lyon RA. Glennon RA, et al. Among authors: smith jd. J Med Chem. 1989 Aug;32(8):1921-6. doi: 10.1021/jm00128a039. J Med Chem. 1989. PMID: 2754715

5

Mesoionic xanthine analogues: phosphodiesterase inhibitory and hypotensive activity.

Glennon RA, Rogers ME, Smith JD, El-Said MK, Egle JL. Glennon RA, et al. Among authors: smith jd. J Med Chem. 1981 Jun;24(6):658-61. doi: 10.1021/jm00138a002. J Med Chem. 1981. PMID: 6265635

6

Mesoionic purinone analogues as inhibitors of cyclic-AMP phosphodiesterase: a comparison of several ring systems.

Rogers ME, Glennon RA, Smith JD, Boots MR, Nanavati N, Maconaughey E, Aub D, Thomas S, Bass RG, Mbagwu G. Rogers ME, et al. Among authors: smith jd. J Med Chem. 1981 Nov;24(11):1284-7. doi: 10.1021/jm00143a004. J Med Chem. 1981. PMID: 6273558

7

4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor.

Leeson PD, Carling RW, Moore KW, Moseley AM, Smith JD, Stevenson G, Chan T, Baker R, Foster AC, Grimwood S, et al. Leeson PD, et al. Among authors: smith jd. J Med Chem. 1992 May 29;35(11):1954-68. doi: 10.1021/jm00089a004. J Med Chem. 1992. PMID: 1534584

8

3-Nitro-3,4-dihydro-2(1H)-quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.

Carling RW, Leeson PD, Moore KW, Smith JD, Moyes CR, Mawer IM, Thomas S, Chan T, Baker R, Foster AC, et al. Carling RW, et al. Among authors: smith jd. J Med Chem. 1993 Oct 29;36(22):3397-408. doi: 10.1021/jm00074a021. J Med Chem. 1993. PMID: 8230130

9

Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel.

Leeson PD, Carling RW, James K, Smith JD, Moore KW, Wong EH, Baker R. Leeson PD, et al. Among authors: smith jd. J Med Chem. 1990 May;33(5):1296-305. doi: 10.1021/jm00167a005. J Med Chem. 1990. PMID: 1691788

10

Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.

Liang J, van Abbema A, Balazs M, Barrett K, Berezhkovsky L, Blair W, Chang C, Delarosa D, DeVoss J, Driscoll J, Eigenbrot C, Ghilardi N, Gibbons P, Halladay J, Johnson A, Kohli PB, Lai Y, Liu Y, Lyssikatos J, Mantik P, Menghrajani K, Murray J, Peng I, Sambrone A, Shia S, Shin Y, Smith J, Sohn S, Tsui V, Ultsch M, Wu LC, Xiao Y, Yang W, Young J, Zhang B, Zhu BY, Magnuson S. Liang J, et al. J Med Chem. 2013 Jun 13;56(11):4521-36. doi: 10.1021/jm400266t. Epub 2013 May 29. J Med Chem. 2013. PMID: 23668484

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