Smith R - Search Results

1

MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.

Kozlowski M, Corujo D, Hothorn M, Guberovic I, Mandemaker IK, Blessing C, Sporn J, Gutierrez-Triana A, Smith R, Portmann T, Treier M, Scheffzek K, Huet S, Timinszky G, Buschbeck M, Ladurner AG. Kozlowski M, et al. Among authors: smith r. EMBO Rep. 2018 Oct;19(10):e44445. doi: 10.15252/embr.201744445. Epub 2018 Sep 3. EMBO Rep. 2018. PMID: 30177554 Free PMC article.

2

The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage.

Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh HR, Kozlowski M, Bultmann S, Ladurner AG, Timinszky G, Huet S. Sellou H, et al. Among authors: smith r. Mol Biol Cell. 2016 Dec 1;27(24):3791-3799. doi: 10.1091/mbc.E16-05-0269. Epub 2016 Oct 12. Mol Biol Cell. 2016. PMID: 27733626 Free PMC article.

3

Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair.

Lebeaupin T, Smith R, Huet S, Timinszky G. Lebeaupin T, et al. Among authors: smith r. Methods Mol Biol. 2017;1608:165-183. doi: 10.1007/978-1-4939-6993-7_12. Methods Mol Biol. 2017. PMID: 28695510

4

CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation.

Smith R, Sellou H, Chapuis C, Huet S, Timinszky G. Smith R, et al. Nucleic Acids Res. 2018 Jul 6;46(12):6087-6098. doi: 10.1093/nar/gky334. Nucleic Acids Res. 2018. PMID: 29733391 Free PMC article.

5

Monitoring Poly(ADP-Ribosyl)ation in Response to DNA Damage in Live Cells Using Fluorescently Tagged Macrodomains.

Smith R, Timinszky G. Smith R, et al. Methods Mol Biol. 2018;1813:11-24. doi: 10.1007/978-1-4939-8588-3_2. Methods Mol Biol. 2018. PMID: 30097858

6

Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.

Pfitzer L, Moser C, Gegenfurtner F, Arner A, Foerster F, Atzberger C, Zisis T, Kubisch-Dohmen R, Busse J, Smith R, Timinszky G, Kalinina OV, Müller R, Wagner E, Vollmar AM, Zahler S. Pfitzer L, et al. Among authors: smith r. Cell Death Dis. 2019 Apr 3;10(4):302. doi: 10.1038/s41419-019-1546-9. Cell Death Dis. 2019. PMID: 30944311 Free PMC article.

7

Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage.

Smith R, Lebeaupin T, Juhász S, Chapuis C, D'Augustin O, Dutertre S, Burkovics P, Biertümpfel C, Timinszky G, Huet S. Smith R, et al. Nucleic Acids Res. 2019 Dec 2;47(21):11250-11267. doi: 10.1093/nar/gkz820. Nucleic Acids Res. 2019. PMID: 31566235 Free PMC article.

8

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

Rother MB, Pellegrino S, Smith R, Gatti M, Meisenberg C, Wiegant WW, Luijsterburg MS, Imhof R, Downs JA, Vertegaal ACO, Huet S, Altmeyer M, van Attikum H. Rother MB, et al. Among authors: smith r. Nat Commun. 2020 Nov 13;11(1):5775. doi: 10.1038/s41467-020-19502-5. Nat Commun. 2020. PMID: 33188175 Free PMC article.

9

The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment.

Juhász S, Smith R, Schauer T, Spekhardt D, Mamar H, Zentout S, Chapuis C, Huet S, Timinszky G. Juhász S, et al. Among authors: smith r. Sci Adv. 2020 Dec 18;6(51):eabb8626. doi: 10.1126/sciadv.abb8626. Print 2020 Dec. Sci Adv. 2020. PMID: 33355125 Free article.

10

Serine-linked PARP1 auto-modification controls PARP inhibitor response.

Prokhorova E, Zobel F, Smith R, Zentout S, Gibbs-Seymour I, Schützenhofer K, Peters A, Groslambert J, Zorzini V, Agnew T, Brognard J, Nielsen ML, Ahel D, Huet S, Suskiewicz MJ, Ahel I. Prokhorova E, et al. Among authors: smith r. Nat Commun. 2021 Jul 1;12(1):4055. doi: 10.1038/s41467-021-24361-9. Nat Commun. 2021. PMID: 34210965 Free PMC article.

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