Snyder JP - Search Results

1

Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators.

Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC, Traynelis SF. Acker TM, et al. Among authors: snyder jp. Mol Pharmacol. 2011 Nov;80(5):782-95. doi: 10.1124/mol.111.073239. Epub 2011 Aug 1. Mol Pharmacol. 2011. PMID: 21807990 Free PMC article.

2

Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists.

Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, Liotta DC, Traynelis SF, Snyder JP. Tahirovic YA, et al. Among authors: snyder jp. J Med Chem. 2008 Sep 25;51(18):5506-21. doi: 10.1021/jm8002153. J Med Chem. 2008. PMID: 18800760 Free PMC article.

3

The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors.

Yuan H, Vance KM, Junge CE, Geballe MT, Snyder JP, Hepler JR, Yepes M, Low CM, Traynelis SF. Yuan H, et al. Among authors: snyder jp. J Biol Chem. 2009 May 8;284(19):12862-73. doi: 10.1074/jbc.M805123200. Epub 2009 Feb 24. J Biol Chem. 2009. PMID: 19240037 Free PMC article.

4

Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.

Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P, Vellano KM, Lewis I, Kurtkaya S, Du Y, Qui M, Murphy TJ, Snyder JP, Bräuner-Osborne H, Traynelis SF. Hansen KB, et al. Among authors: snyder jp. J Pharmacol Exp Ther. 2010 Jun;333(3):650-62. doi: 10.1124/jpet.110.166256. Epub 2010 Mar 2. J Pharmacol Exp Ther. 2010. PMID: 20197375 Free PMC article.

5

Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.

Burger PB, Yuan H, Karakas E, Geballe M, Furukawa H, Liotta DC, Snyder JP, Traynelis SF. Burger PB, et al. Among authors: snyder jp. Mol Pharmacol. 2012 Aug;82(2):344-59. doi: 10.1124/mol.112.078568. Epub 2012 May 17. Mol Pharmacol. 2012. PMID: 22596351 Free PMC article.

6

Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists.

Acker TM, Khatri A, Vance KM, Slabber C, Bacsa J, Snyder JP, Traynelis SF, Liotta DC. Acker TM, et al. Among authors: snyder jp. J Med Chem. 2013 Aug 22;56(16):6434-56. doi: 10.1021/jm400652r. Epub 2013 Aug 2. J Med Chem. 2013. PMID: 23909910 Free PMC article.

7

Regulation of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor function by protein kinase C at serine-818 and threonine-840.

Jenkins MA, Wells G, Bachman J, Snyder JP, Jenkins A, Huganir RL, Oswald RE, Traynelis SF. Jenkins MA, et al. Among authors: snyder jp. Mol Pharmacol. 2014 Apr;85(4):618-29. doi: 10.1124/mol.113.091488. Epub 2014 Jan 22. Mol Pharmacol. 2014. PMID: 24452473 Free PMC article.

8

Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.

Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF. Khatri A, et al. Among authors: snyder jp. Mol Pharmacol. 2014 Nov;86(5):548-60. doi: 10.1124/mol.114.094516. Epub 2014 Sep 9. Mol Pharmacol. 2014. PMID: 25205677 Free PMC article.

9

The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening.

Wells G, Yuan H, McDaniel MJ, Kusumoto H, Snyder JP, Liotta DC, Traynelis SF. Wells G, et al. Among authors: snyder jp. Proteins. 2018 Dec;86(12):1265-1276. doi: 10.1002/prot.25595. Epub 2018 Oct 5. Proteins. 2018. PMID: 30168177 Free PMC article.

10

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors.

Erreger K, Geballe MT, Kristensen A, Chen PE, Hansen KB, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jørgensen L, Clausen RP, Wyllie DJ, Snyder JP, Traynelis SF. Erreger K, et al. Among authors: snyder jp. Mol Pharmacol. 2007 Oct;72(4):907-20. doi: 10.1124/mol.107.037333. Epub 2007 Jul 10. Mol Pharmacol. 2007. PMID: 17622578

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