Spada A - Search Results

1

Restenosis following angioplasty in the swine coronary artery is inhibited by an orally active PDGF-receptor tyrosine kinase inhibitor, RPR101511A.

Bilder G, Wentz T, Leadley R, Amin D, Byan L, O'Conner B, Needle S, Galczenski H, Bostwick J, Kasiewski C, Myers M, Spada A, Merkel L, Ly C, Persons P, Page K, Perrone M, Dunwiddie C. Bilder G, et al. Among authors: spada a. Circulation. 1999 Jun 29;99(25):3292-9. doi: 10.1161/01.cir.99.25.3292. Circulation. 1999. PMID: 10385505

2

Stent-induced restenosis in the swine coronary artery is inhibited by a platelet-derived growth factor receptor tyrosine kinase inhibitor, TKI963.

Bilder G, Amin D, Morgan L, McVey M, Needle S, Galczenski H, Leadley R, He W, Myers M, Spada A, Luo Y, Natajaran C, Perrone M. Bilder G, et al. Among authors: spada a. J Cardiovasc Pharmacol. 2003 Jun;41(6):817-29. doi: 10.1097/00005344-200306000-00001. J Cardiovasc Pharmacol. 2003. PMID: 12775958

3

Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor.

He W, Myers MR, Hanney B, Spada AP, Bilder G, Galzcinski H, Amin D, Needle S, Page K, Jayyosi Z, Perrone MH. He W, et al. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3097-100. doi: 10.1016/s0960-894x(03)00655-3. Bioorg Med Chem Lett. 2003. PMID: 12941342

4

RPR120844, a novel, specific inhibitor of coagulation factor Xa inhibits venous thrombosis in the rabbit.

Bostwick JS, Bentley R, Morgan S, Brown K, Chu V, Ewing WR, Spada AP, Pauls H, Perrone MH, Dunwiddie CT, Leadley RJ Jr. Bostwick JS, et al. Among authors: spada ap. Thromb Haemost. 1999 Jan;81(1):157-60. Thromb Haemost. 1999. PMID: 10348709

5

Aminoisoquinolines: design and synthesis of an orally active benzamidine isostere for the inhibition of factor XA.

Choi-Sledeski YM, Becker MR, Green DM, Davis R, Ewing WR, Mason HJ, Ly C, Spada A, Liang G, Cheney D, Barton J, Chu V, Brown K, Colussi D, Bentley R, Leadley R, Dunwiddie C, Pauls HW. Choi-Sledeski YM, et al. Among authors: spada a. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2539-44. doi: 10.1016/s0960-894x(99)00421-7. Bioorg Med Chem Lett. 1999. PMID: 10498204

6

Kinetic analysis of the inhibition of the epidermal growth factor receptor tyrosine kinase by Lavendustin-A and its analogue.

Hsu CY, Persons PE, Spada AP, Bednar RA, Levitzki A, Zilberstein A. Hsu CY, et al. Among authors: spada ap. J Biol Chem. 1991 Nov 5;266(31):21105-12. J Biol Chem. 1991. PMID: 1939153 Free article.

7

Pharmacodynamic activity and antithrombotic efficacy of RPR120844, a novel inhibitor of coagulation factor Xa.

Leadley RJ Jr, Morgan SR, Bentley R, Bostwick JS, Kasiewski CJ, Heran C, Chu V, Brown K, Moxey P, Ewing WR, Pauls H, Spada AP, Perrone MH, Dunwiddie CT. Leadley RJ Jr, et al. Among authors: spada ap. J Cardiovasc Pharmacol. 1999 Dec;34(6):791-9. doi: 10.1097/00005344-199912000-00004. J Cardiovasc Pharmacol. 1999. PMID: 10598121

8

In vitro characterization of a novel factor Xa inhibitor, RPR 130737.

Chu V, Brown K, Colussi D, Choi YM, Green D, Pauls HW, Spada AP, Perrone MH, Leadley RJ Jr, Dunwiddie CT. Chu V, et al. Among authors: spada ap. Thromb Res. 2000 Jul 1;99(1):71-82. doi: 10.1016/s0049-3848(00)00227-9. Thromb Res. 2000. PMID: 11012377

9

Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 1: SAR exploration and effective bioisosteric replacement of a phenyl substituent.

Myers MR, He W, Hanney B, Setzer N, Maguire MP, Zulli A, Bilder G, Galzcinski H, Amin D, Needle S, Spada AP. Myers MR, et al. Among authors: spada ap. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3091-5. doi: 10.1016/s0960-894x(03)00654-1. Bioorg Med Chem Lett. 2003. PMID: 12941341

10

Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa.

Ewing WR, Becker MR, Manetta VE, Davis RS, Pauls HW, Mason H, Choi-Sledeski YM, Green D, Cha D, Spada AP, Cheney DL, Mason JS, Maignan S, Guilloteau JP, Brown K, Colussi D, Bentley R, Bostwick J, Kasiewski CJ, Morgan SR, Leadley RJ, Dunwiddie CT, Perrone MH, Chu V. Ewing WR, et al. Among authors: spada ap. J Med Chem. 1999 Sep 9;42(18):3557-71. doi: 10.1021/jm990040h. J Med Chem. 1999. PMID: 10479288

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

684 results

Search Page