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Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function.
Link VM, Duttke SH, Chun HB, Holtman IR, Westin E, Hoeksema MA, Abe Y, Skola D, Romanoski CE, Tao J, Fonseca GJ, Troutman TD, Spann NJ, Strid T, Sakai M, Yu M, Hu R, Fang R, Metzler D, Ren B, Glass CK. Link VM, et al. Among authors: spann nj. Cell. 2018 Jun 14;173(7):1796-1809.e17. doi: 10.1016/j.cell.2018.04.018. Epub 2018 May 17. Cell. 2018. PMID: 29779944 Free PMC article.
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.
Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. Fan W, et al. Among authors: spann nj. EMBO J. 2010 Dec 15;29(24):4223-36. doi: 10.1038/emboj.2010.268. Epub 2010 Nov 2. EMBO J. 2010. PMID: 21045807 Free PMC article.
Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.
Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH Jr, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. Spann NJ, et al. Cell. 2012 Sep 28;151(1):138-52. doi: 10.1016/j.cell.2012.06.054. Cell. 2012. PMID: 23021221 Free PMC article.
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P. Blanc M, et al. Among authors: spann nj. Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27. Immunity. 2013. PMID: 23273843 Free PMC article.
41 results