Spears CP - Search Results

1

Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells.

Yang L, Chiang Y, Lenz HJ, Danenberg KD, Spears CP, Gordon EM, Anderson WF, Parekh D. Yang L, et al. Among authors: spears cp. Hum Gene Ther. 1998 Mar 20;9(5):719-28. doi: 10.1089/hum.1998.9.5-719. Hum Gene Ther. 1998. PMID: 9551619

2

Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial.

Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A, et al. Leichman L, et al. Among authors: spears cp. Eur J Cancer. 1995 Jul-Aug;31A(7-8):1306-10. doi: 10.1016/0959-8049(95)00326-e. Eur J Cancer. 1995. PMID: 7577041 Clinical Trial.

3

Restoration of wild-type p53 activity in p53-null HL-60 cells confers multidrug sensitivity.

Ju JF, Banerjee D, Lenz HJ, Danenberg KD, Schmittgen TC, Spears CP, Schönthal AH, Manno DJ, Hochhauser D, Bertino JR, Danenberg PV. Ju JF, et al. Among authors: spears cp. Clin Cancer Res. 1998 May;4(5):1315-22. Clin Cancer Res. 1998. PMID: 9607592

4

Transfection of wild-type but not mutant p53 induces early monocytic differentiation in HL60 cells and increases their sensitivity to stress.

Banerjee D, Lenz HJ, Schnieders B, Manno DJ, Ju JF, Spears CP, Hochhauser D, Danenberg K, Danenberg P, Bertino JR. Banerjee D, et al. Among authors: spears cp. Cell Growth Differ. 1995 Nov;6(11):1405-13. Cell Growth Differ. 1995. PMID: 8562479

5

Clinical resistance to antimetabolites.

Spears CP. Spears CP. Hematol Oncol Clin North Am. 1995 Apr;9(2):397-413. Hematol Oncol Clin North Am. 1995. PMID: 7642470 Review.

6

Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil.

Spears CP, Gustavsson BG, Berne M, Frösing R, Bernstein L, Hayes AA. Spears CP, et al. Cancer Res. 1988 Oct 15;48(20):5894-900. Cancer Res. 1988. PMID: 3167844

7

Biological modification of protracted infusion of 5-fluorouracil with weekly leucovorin. A dose seeking clinical trial for patients with disseminated gastrointestinal cancers.

Leichman CG, Leichman L, Spears CP, Rosen PJ, Muggia F, Jeffers S, Waugh W. Leichman CG, et al. Among authors: spears cp. Cancer Chemother Pharmacol. 1990;26(1):57-61. doi: 10.1007/BF02940295. Cancer Chemother Pharmacol. 1990. PMID: 2182214 Clinical Trial.

8

Prolonged continuous infusion of fluorouracil with weekly bolus leucovorin: a phase II study in patients with disseminated colorectal cancer.

Leichman CG, Leichman L, Spears CP, Rosen PJ, Jeffers S, Groshen S. Leichman CG, et al. Among authors: spears cp. J Natl Cancer Inst. 1993 Jan 6;85(1):41-4. doi: 10.1093/jnci/85.1.41. J Natl Cancer Inst. 1993. PMID: 8416255 Clinical Trial.

9

Phase I and pharmacologic study of i.v. hydroxyurea infusion given with i.p. 5-fluoro-2'-deoxyuridine and leucovorin.

Garcia AA, Muggia FM, Spears CP, Jeffers S, Silberman H, Pujari M, Koda RT. Garcia AA, et al. Among authors: spears cp. Anticancer Drugs. 2001 Jul;12(6):505-11. doi: 10.1097/00001813-200107000-00003. Anticancer Drugs. 2001. PMID: 11459996 Clinical Trial.

10

Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program.

Leichman L, Silberman H, Leichman CG, Spears CP, Ray M, Muggia FM, Kiyabu M, Radin R, Laine L, Stain S, et al. Leichman L, et al. Among authors: spears cp. J Clin Oncol. 1992 Dec;10(12):1933-42. doi: 10.1200/JCO.1992.10.12.1933. J Clin Oncol. 1992. PMID: 1453207 Clinical Trial.

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