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Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism.
Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Thompson AJ, et al. Among authors: spears rj. Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5378-82. doi: 10.1002/anie.201410502. Epub 2015 Mar 13. Angew Chem Int Ed Engl. 2015. PMID: 25772148
Corrigendum: Evidence for a Boat Conformation at the Transition State of GH76 α-1,6-Mannanases--Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism.
Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Thompson AJ, et al. Among authors: spears rj. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):1949. doi: 10.1002/anie.201511540. Angew Chem Int Ed Engl. 2016. PMID: 26836331 No abstract available.
Tyrosine bioconjugation - an emergent alternative.
Szijj PA, Kostadinova KA, Spears RJ, Chudasama V. Szijj PA, et al. Among authors: spears rj. Org Biomol Chem. 2020 Nov 28;18(44):9018-9028. doi: 10.1039/d0ob01912g. Epub 2020 Nov 3. Org Biomol Chem. 2020. PMID: 33141139 Free PMC article.
A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations.
Keenan T, Spears RJ, Akkad S, Mahon CS, Hatton NE, Walton J, Noble A, Yates ND, Baumann CG, Parkin A, Signoret N, Fascione MA. Keenan T, et al. Among authors: spears rj. ACS Chem Biol. 2021 Nov 19;16(11):2387-2400. doi: 10.1021/acschembio.1c00531. Epub 2021 Nov 9. ACS Chem Biol. 2021. PMID: 34751550 Free article.
23 results