Spence HJ - Search Results

1

The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migration.

Zech T, Calaminus SD, Caswell P, Spence HJ, Carnell M, Insall RH, Norman J, Machesky LM. Zech T, et al. Among authors: spence hj. J Cell Sci. 2011 Nov 15;124(Pt 22):3753-9. doi: 10.1242/jcs.080986. Epub 2011 Nov 23. J Cell Sci. 2011. PMID: 22114305 Free PMC article.

2

Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.

Caswell PT, Spence HJ, Parsons M, White DP, Clark K, Cheng KW, Mills GB, Humphries MJ, Messent AJ, Anderson KI, McCaffrey MW, Ozanne BW, Norman JC. Caswell PT, et al. Among authors: spence hj. Dev Cell. 2007 Oct;13(4):496-510. doi: 10.1016/j.devcel.2007.08.012. Dev Cell. 2007. PMID: 17925226 Free article.

3

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion.

Li A, Dawson JC, Forero-Vargas M, Spence HJ, Yu X, König I, Anderson K, Machesky LM. Li A, et al. Among authors: spence hj. Curr Biol. 2010 Feb 23;20(4):339-45. doi: 10.1016/j.cub.2009.12.035. Epub 2010 Feb 4. Curr Biol. 2010. PMID: 20137952 Free PMC article.

4

Functional analysis of Dictyostelium IBARa reveals a conserved role of the I-BAR domain in endocytosis.

Veltman DM, Auciello G, Spence HJ, Machesky LM, Rappoport JZ, Insall RH. Veltman DM, et al. Among authors: spence hj. Biochem J. 2011 May 15;436(1):45-52. doi: 10.1042/BJ20101684. Biochem J. 2011. PMID: 21401524

5

Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.

Dawson JC, Bruche S, Spence HJ, Braga VM, Machesky LM. Dawson JC, et al. Among authors: spence hj. PLoS One. 2012;7(3):e31141. doi: 10.1371/journal.pone.0031141. Epub 2012 Mar 27. PLoS One. 2012. PMID: 22479308 Free PMC article.

6

Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions.

Spence HJ, Timpson P, Tang HR, Insall RH, Machesky LM. Spence HJ, et al. Biochem J. 2012 Nov 15;448(1):35-42. doi: 10.1042/BJ20112206. Biochem J. 2012. PMID: 22909346 Free PMC article.

7

N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.

Yu X, Zech T, McDonald L, Gonzalez EG, Li A, Macpherson I, Schwarz JP, Spence H, Futó K, Timpson P, Nixon C, Ma Y, Anton IM, Visegrády B, Insall RH, Oien K, Blyth K, Norman JC, Machesky LM. Yu X, et al. J Cell Biol. 2012 Oct 29;199(3):527-44. doi: 10.1083/jcb.201203025. Epub 2012 Oct 22. J Cell Biol. 2012. PMID: 23091069 Free PMC article.

8

Loss of Scar/WAVE complex promotes N-WASP- and FAK-dependent invasion.

Tang H, Li A, Bi J, Veltman DM, Zech T, Spence HJ, Yu X, Timpson P, Insall RH, Frame MC, Machesky LM. Tang H, et al. Among authors: spence hj. Curr Biol. 2013 Jan 21;23(2):107-17. doi: 10.1016/j.cub.2012.11.059. Epub 2012 Dec 27. Curr Biol. 2013. PMID: 23273897 Free article.

9

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

Tyrrell BJ, Woodham EF, Spence HJ, Strathdee D, Insall RH, Machesky LM. Tyrrell BJ, et al. Among authors: spence hj. Pigment Cell Melanoma Res. 2016 Sep;29(5):559-71. doi: 10.1111/pcmr.12506. Pigment Cell Melanoma Res. 2016. PMID: 27390154 Free PMC article.

10

Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.

Woodham EF, Paul NR, Tyrrell B, Spence HJ, Swaminathan K, Scribner MR, Giampazolias E, Hedley A, Clark W, Kage F, Marston DJ, Hahn KM, Tait SW, Larue L, Brakebusch CH, Insall RH, Machesky LM. Woodham EF, et al. Among authors: spence hj. Curr Biol. 2017 Mar 6;27(5):624-637. doi: 10.1016/j.cub.2017.01.033. Epub 2017 Feb 23. Curr Biol. 2017. PMID: 28238662 Free PMC article.

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