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Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.
Liu L, Malagu K, Haughan AF, Khetarpal V, Stott AJ, Esmieu W, Vater HD, Webster SJ, Van de Poël AJ, Clissold C, Cosgrove B, Sutton B, Spencer JA, Breccia P, Gancia E, Bonomo S, Ladduwahetty T, Lazari O, Patel H, Atton HC, Clifton S, Mota DM, Magnani D, O'Neill A, Stebbeds M, Macabuag N, Todd D, Herva ME, Mitchell P, Visser M, Compte Sancerni S, Grand Moursel L, da Silva M, Kritikou E, Heikkinen TT, Bolkvadze T, Fodale V, Spadafora D, Daldin M, Bresciani A, Mangette JE, Doherty EM, Lee MR, Herbst T, Monteagudo E, Macdonald D, Plotnikov NV, Chambers M, McAllister G, Muňoz-Sanjuan I, Dominguez C. Liu L, et al. Among authors: spencer ja. J Med Chem. 2023 Sep 28;66(18):13205-13246. doi: 10.1021/acs.jmedchem.3c01173. Epub 2023 Sep 15. J Med Chem. 2023. PMID: 37712656
Multiple models for outbreak decision support in the face of uncertainty.
Shea K, Borchering RK, Probert WJM, Howerton E, Bogich TL, Li SL, van Panhuis WG, Viboud C, Aguás R, Belov AA, Bhargava SH, Cavany SM, Chang JC, Chen C, Chen J, Chen S, Chen Y, Childs LM, Chow CC, Crooker I, Del Valle SY, España G, Fairchild G, Gerkin RC, Germann TC, Gu Q, Guan X, Guo L, Hart GR, Hladish TJ, Hupert N, Janies D, Kerr CC, Klein DJ, Klein EY, Lin G, Manore C, Meyers LA, Mittler JE, Mu K, Núñez RC, Oidtman RJ, Pasco R, Pastore Y Piontti A, Paul R, Pearson CAB, Perdomo DR, Perkins TA, Pierce K, Pillai AN, Rael RC, Rosenfeld K, Ross CW, Spencer JA, Stoltzfus AB, Toh KB, Vattikuti S, Vespignani A, Wang L, White LJ, Xu P, Yang Y, Yogurtcu ON, Zhang W, Zhao Y, Zou D, Ferrari MJ, Pannell D, Tildesley MJ, Seifarth J, Johnson E, Biggerstaff M, Johansson MA, Slayton RB, Levander JD, Stazer J, Kerr J, Runge MC. Shea K, et al. Among authors: spencer ja. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2207537120. doi: 10.1073/pnas.2207537120. Epub 2023 Apr 25. Proc Natl Acad Sci U S A. 2023. PMID: 37098064 Free PMC article.
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L, Booth GT, Geng F, Liu Y, Gomez-Salinero JM, Shieh JH, Redmond D, Xiang JZ, Josefowicz SZ, Trapnell C, Spencer JA, Zangi L, Hadland B, Dick JE, Xie SZ, Rafii S. Itkin T, et al. Among authors: spencer ja. bioRxiv [Preprint]. 2023 Mar 29:2023.03.27.534417. doi: 10.1101/2023.03.27.534417. bioRxiv. 2023. PMID: 37034724 Free PMC article. Preprint.
Distinguishing viruses responsible for influenza-like illness.
Spencer JA, Shutt DP, Moser SK, Clegg H, Wearing HJ, Mukundan H, Manore CA. Spencer JA, et al. J Theor Biol. 2022 Jul 21;545:111145. doi: 10.1016/j.jtbi.2022.111145. Epub 2022 Apr 29. J Theor Biol. 2022. PMID: 35490763 Free article.
The Thrower's Shoulder.
Medina G, Bartolozzi AR 3rd, Spencer JA, Morgan C. Medina G, et al. Among authors: spencer ja. JBJS Rev. 2022 Mar 18;10(3). doi: 10.2106/JBJS.RVW.21.00194. JBJS Rev. 2022. PMID: 35302966 Review.
362 results