Sperling SR - Search Results

1

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.

Cui H, Yi H, Bao H, Tan Y, Tian C, Shi X, Gan D, Zhang B, Liang W, Chen R, Zhu Q, Fang L, Gao X, Huang H, Tian R, Sperling SR, Hu Y, Chen W. Cui H, et al. Among authors: sperling sr. Nat Commun. 2022 Aug 9;13(1):4680. doi: 10.1038/s41467-022-32472-0. Nat Commun. 2022. PMID: 35945219 Free PMC article.

2

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.

Cui H, Schlesinger J, Schoenhals S, Tönjes M, Dunkel I, Meierhofer D, Cano E, Schulz K, Berger MF, Haack T, Abdelilah-Seyfried S, Bulyk ML, Sauer S, Sperling SR. Cui H, et al. Among authors: sperling sr. Nucleic Acids Res. 2016 Apr 7;44(6):2538-53. doi: 10.1093/nar/gkv1244. Epub 2015 Nov 17. Nucleic Acids Res. 2016. PMID: 26582913 Free PMC article.

3

Comparative DNA methylation and gene expression analysis identifies novel genes for structural congenital heart diseases.

Grunert M, Dorn C, Cui H, Dunkel I, Schulz K, Schoenhals S, Sun W, Berger F, Chen W, Sperling SR. Grunert M, et al. Among authors: sperling sr. Cardiovasc Res. 2016 Oct;112(1):464-77. doi: 10.1093/cvr/cvw195. Epub 2016 Aug 5. Cardiovasc Res. 2016. PMID: 27496870

4

Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.

Cui H, Bansal V, Grunert M, Malecova B, Dall'Agnese A, Latella L, Gatto S, Ryan T, Schulz K, Chen W, Dorn C, Puri PL, Sperling SR. Cui H, et al. Among authors: sperling sr. PLoS One. 2017 Jun 13;12(6):e0179464. doi: 10.1371/journal.pone.0179464. eCollection 2017. PLoS One. 2017. PMID: 28609469 Free PMC article.

5

Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation.

Grunert M, Appelt S, Schönhals S, Mika K, Cui H, Cooper A, Cyganek L, Guan K, Sperling SR. Grunert M, et al. Among authors: sperling sr. Sci Rep. 2020 Jul 2;10(1):10921. doi: 10.1038/s41598-020-67872-z. Sci Rep. 2020. PMID: 32616843 Free PMC article.

6

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

Lange M, Kaynak B, Forster UB, Tönjes M, Fischer JJ, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S, Sperling S. Lange M, et al. Genes Dev. 2008 Sep 1;22(17):2370-84. doi: 10.1101/gad.471408. Genes Dev. 2008. PMID: 18765789 Free PMC article.

7

CRISPR correction of the PRKAG2 gene mutation in the patient's induced pluripotent stem cell-derived cardiomyocytes eliminates electrophysiological and structural abnormalities.

Ben Jehuda R, Eisen B, Shemer Y, Mekies LN, Szantai A, Reiter I, Cui H, Guan K, Haron-Khun S, Freimark D, Sperling SR, Gherghiceanu M, Arad M, Binah O. Ben Jehuda R, et al. Among authors: sperling sr. Heart Rhythm. 2018 Feb;15(2):267-276. doi: 10.1016/j.hrthm.2017.09.024. Epub 2017 Sep 14. Heart Rhythm. 2018. PMID: 28917552

8

Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.

Jürchott K, Kuban RJ, Krech T, Blüthgen N, Stein U, Walther W, Friese C, Kiełbasa SM, Ungethüm U, Lund P, Knösel T, Kemmner W, Morkel M, Fritzmann J, Schlag PM, Birchmeier W, Krueger T, Sperling S, Sers C, Royer HD, Herzel H, Schäfer R. Jürchott K, et al. PLoS Genet. 2010 Dec 2;6(12):e1001231. doi: 10.1371/journal.pgen.1001231. PLoS Genet. 2010. PMID: 21170361 Free PMC article.

9

Dynamics of Srf, p300 and histone modifications during cardiac maturation in mouse.

Schueler M, Zhang Q, Schlesinger J, Tönjes M, Sperling SR. Schueler M, et al. Among authors: sperling sr. Mol Biosyst. 2012 Feb;8(2):495-503. doi: 10.1039/c1mb05363a. Epub 2011 Nov 18. Mol Biosyst. 2012. PMID: 22101280

10

The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs.

Schlesinger J, Schueler M, Grunert M, Fischer JJ, Zhang Q, Krueger T, Lange M, Tönjes M, Dunkel I, Sperling SR. Schlesinger J, et al. Among authors: sperling sr. PLoS Genet. 2011 Feb;7(2):e1001313. doi: 10.1371/journal.pgen.1001313. Epub 2011 Feb 17. PLoS Genet. 2011. PMID: 21379568 Free PMC article.

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