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Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis.
Wang F, Van Brocklyn JR, Hobson JP, Movafagh S, Zukowska-Grojec Z, Milstien S, Spiegel S. Wang F, et al. Among authors: spiegel s. J Biol Chem. 1999 Dec 10;274(50):35343-50. doi: 10.1074/jbc.274.50.35343. J Biol Chem. 1999. PMID: 10585401 Free article.
In agreement with previous findings in human breast cancer cells (Wang, F., Nohara, K., Olivera, O., Thompson, E. W., and Spiegel, S. (1999) Exp. Cell Res. 247, 17-28), SPP, at micromolar concentrations, inhibited chemotaxis of both vector- and EDG-1-overexpressing …
In agreement with previous findings in human breast cancer cells (Wang, F., Nohara, K., Olivera, O., Thompson, E. W., and Spiegel, …
Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation.
Desai NN, Zhang H, Olivera A, Mattie ME, Spiegel S. Desai NN, et al. Among authors: spiegel s. J Biol Chem. 1992 Nov 15;267(32):23122-8. J Biol Chem. 1992. PMID: 1429659 Free article.
Sphingosine and sphingosine-1-phosphate, metabolites of membrane sphingolipids, have recently been shown to stimulate release of calcium from internal sources and to increase proliferation of quiescent Swiss 3T3 fibroblasts (Zhang, H., Desai, N. N., Olivera, A., Seki, T., Brooker …
Sphingosine and sphingosine-1-phosphate, metabolites of membrane sphingolipids, have recently been shown to stimulate release of calcium fro …
Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation.
Zhang H, Desai NN, Olivera A, Seki T, Brooker G, Spiegel S. Zhang H, et al. Among authors: spiegel s. J Cell Biol. 1991 Jul;114(1):155-67. doi: 10.1083/jcb.114.1.155. J Cell Biol. 1991. PMID: 2050740 Free PMC article.
Sphingosine, a metabolite of membrane sphingolipids, regulates proliferation of quiescent Swiss 3T3 fibroblasts (Zhang, H., N. E. Buckley, K. Gibson. and S. Spiegel. 1990. J. Biol. Chem. 265:76-81). The present study provides new insights into the formation and func …
Sphingosine, a metabolite of membrane sphingolipids, regulates proliferation of quiescent Swiss 3T3 fibroblasts (Zhang, H., N. E. Buckley, K …
Increases in phosphatidic acid levels accompany sphingosine-stimulated proliferation of quiescent Swiss 3T3 cells.
Zhang H, Desai NN, Murphey JM, Spiegel S. Zhang H, et al. Among authors: spiegel s. J Biol Chem. 1990 Dec 5;265(34):21309-16. J Biol Chem. 1990. PMID: 2250025 Free article.
Sphingosine, a breakdown product of cellular sphingolipids, has recently been shown to stimulate DNA synthesis and act synergistically with known growth factors to induce proliferation of quiescent Swiss 3T3 fibroblasts (Hong, Z., Buckley, N. E., Gibson, K., and Spiegel, …
Sphingosine, a breakdown product of cellular sphingolipids, has recently been shown to stimulate DNA synthesis and act synergistically with …
Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate.
Goodemote KA, Mattie ME, Berger A, Spiegel S. Goodemote KA, et al. Among authors: spiegel s. J Biol Chem. 1995 Apr 28;270(17):10272-7. doi: 10.1074/jbc.270.17.10272. J Biol Chem. 1995. PMID: 7730331 Free article.
Sphingosine 1-phosphate, a sphingolipid metabolite, was previously reported to increase DNA synthesis in quiescent Swiss 3T3 fibroblasts and to induce transient increases in intracellular free calcium (Zhang, H., Desai, N. N., Olivera, A., Seki, T., Brooker, G., and Spiegel …
Sphingosine 1-phosphate, a sphingolipid metabolite, was previously reported to increase DNA synthesis in quiescent Swiss 3T3 fibroblasts and …
491 results