Spiekermann K - Search Results

1

Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group.

Lengfelder E, Hanfstein B, Haferlach C, Braess J, Krug U, Spiekermann K, Haferlach T, Kreuzer KA, Serve H, Horst HA, Schnittger S, Aul C, Schultheis B, Erben P, Schneider S, Müller-Tidow C, Wörmann B, Berdel WE, Sauerland C, Heinecke A, Hehlmann R, Hofmann WK, Hiddemann W, Büchner T; German Acute Myeloid Leukemia Cooperative Group (AMLCG). Lengfelder E, et al. Among authors: spiekermann k. Ann Hematol. 2013 Jan;92(1):41-52. doi: 10.1007/s00277-012-1597-9. Epub 2012 Oct 23. Ann Hematol. 2013. PMID: 23090499 Free PMC article.

2

Combination chemotherapy with CHOP for recurrent thrombotic thrombocytopenic purpura.

Spiekermann K, Wörmann B, Rumpf KW, Hiddemann W. Spiekermann K, et al. Br J Haematol. 1997 Jun;97(3):544-6. doi: 10.1046/j.1365-2141.1997.1022918.x. Br J Haematol. 1997. PMID: 9207396 Free article.

3

Expression of granulocyte colony-stimulating factor- and granulocyte-macrophage colony-stimulating factor-associated signal transduction proteins of the JAK/STAT pathway in normal granulopoiesis and in blast cells of acute myelogenous leukemia.

Biethahn S, Alves F, Wilde S, Hiddemann W, Spiekermann K. Biethahn S, et al. Among authors: spiekermann k. Exp Hematol. 1999 May;27(5):885-94. doi: 10.1016/s0301-472x(99)00017-x. Exp Hematol. 1999. PMID: 10340405 Free article.

4

Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells.

Spiekermann K, Pau M, Schwab R, Schmieja K, Franzrahe S, Hiddemann W. Spiekermann K, et al. Exp Hematol. 2002 Mar;30(3):262-71. doi: 10.1016/s0301-472x(01)00787-1. Exp Hematol. 2002. PMID: 11882364 Free article.

5

The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells.

Spiekermann K, Faber F, Voswinckel R, Hiddemann W. Spiekermann K, et al. Exp Hematol. 2002 Jul;30(7):767-73. doi: 10.1016/s0301-472x(02)00837-8. Exp Hematol. 2002. PMID: 12135675 Free article.

6

A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia.

Spiekermann K, Bagrintseva K, Schoch C, Haferlach T, Hiddemann W, Schnittger S. Spiekermann K, et al. Blood. 2002 Nov 1;100(9):3423-5. doi: 10.1182/blood-2002-03-0953. Blood. 2002. PMID: 12384447 Free article.

7

Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells.

Spiekermann K, Bagrintseva K, Schwab R, Schmieja K, Hiddemann W. Spiekermann K, et al. Clin Cancer Res. 2003 Jun;9(6):2140-50. Clin Cancer Res. 2003. PMID: 12796379

8

Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells.

Bagrintseva K, Schwab R, Kohl TM, Schnittger S, Eichenlaub S, Ellwart JW, Hiddemann W, Spiekermann K. Bagrintseva K, et al. Among authors: spiekermann k. Blood. 2004 Mar 15;103(6):2266-75. doi: 10.1182/blood-2003-05-1653. Epub 2003 Nov 6. Blood. 2004. PMID: 14604974 Free article.

9

KIT exon 8 mutations associated with core-binding factor (CBF)-acute myeloid leukemia (AML) cause hyperactivation of the receptor in response to stem cell factor.

Kohl TM, Schnittger S, Ellwart JW, Hiddemann W, Spiekermann K. Kohl TM, et al. Among authors: spiekermann k. Blood. 2005 Apr 15;105(8):3319-21. doi: 10.1182/blood-2004-06-2068. Epub 2004 Dec 23. Blood. 2005. PMID: 15618474 Free article.

10

[Mutations of the gene coding for the receptor tyrosine kinase FLT3 in acute myeloid leukemia. Significance as the disease-specific molecular marker for diagnosis, prognosis and innovative therapy approaches].

Spiekermann K, Hiddemann W, Schnittger S. Spiekermann K, et al. Dtsch Med Wochenschr. 2005 Apr 22;130(16):1020-5. doi: 10.1055/s-2005-866780. Dtsch Med Wochenschr. 2005. PMID: 15830315 Review. German. No abstract available.

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