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A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death.
Scott DE, Francis-Newton NJ, Marsh ME, Coyne AG, Fischer G, Moschetti T, Bayly AR, Sharpe TD, Haas KT, Barber L, Valenzano CR, Srinivasan R, Huggins DJ, Lee M, Emery A, Hardwick B, Ehebauer M, Dagostin C, Esposito A, Pellegrini L, Perrior T, McKenzie G, Blundell TL, Hyvönen M, Skidmore J, Venkitaraman AR, Abell C. Scott DE, et al. Among authors: srinivasan r. Cell Chem Biol. 2021 Jun 17;28(6):835-847.e5. doi: 10.1016/j.chembiol.2021.02.006. Epub 2021 Mar 3. Cell Chem Biol. 2021. PMID: 33662256 Free PMC article.
Allosteric Small-Molecule Serine/Threonine Kinase Inhibitors.
Panicker RC, Chattopadhaya S, Coyne AG, Srinivasan R. Panicker RC, et al. Among authors: srinivasan r. Adv Exp Med Biol. 2019;1163:253-278. doi: 10.1007/978-981-13-8719-7_11. Adv Exp Med Biol. 2019. PMID: 31707707 Review.
Activity-based fingerprinting of proteases.
Srinivasan R, Huang X, Ng SL, Yao SQ. Srinivasan R, et al. Chembiochem. 2006 Jan;7(1):32-6. doi: 10.1002/cbic.200500340. Chembiochem. 2006. PMID: 16317790 No abstract available.
1,775 results