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Efficient synthesis and biological evaluation of proximicins A, B and C.
Brucoli F, Natoli A, Marimuthu P, Borrello MT, Stapleton P, Gibbons S, Schätzlein A. Brucoli F, et al. Among authors: stapleton p. Bioorg Med Chem. 2012 Mar 15;20(6):2019-24. doi: 10.1016/j.bmc.2012.01.043. Epub 2012 Feb 4. Bioorg Med Chem. 2012. PMID: 22364744
Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels - A Strategy for Brain Cancer Treatments.
Fisusi FA, Siew A, Chooi KW, Okubanjo O, Garrett N, Lalatsa K, Serrano D, Summers I, Moger J, Stapleton P, Satchi-Fainaro R, Schätzlein AG, Uchegbu IF. Fisusi FA, et al. Among authors: stapleton p. Pharm Res. 2016 May;33(5):1289-303. doi: 10.1007/s11095-016-1872-x. Epub 2016 Feb 22. Pharm Res. 2016. PMID: 26903051 Free PMC article.
Regioselective glycosylation of novobiocin alters activity.
Sun G, de Resende PE, Stapleton P, Kuta M, Wang X, Haider S, Yang M. Sun G, et al. Among authors: stapleton p. Carbohydr Res. 2017 Nov 27;452:116-121. doi: 10.1016/j.carres.2017.10.011. Epub 2017 Oct 22. Carbohydr Res. 2017. PMID: 29096184
Boronic acid inhibitors of the class A β-lactamase KPC-2.
Zhou J, Stapleton P, Haider S, Healy J. Zhou J, et al. Among authors: stapleton p. Bioorg Med Chem. 2018 Jul 15;26(11):2921-2927. doi: 10.1016/j.bmc.2018.04.055. Epub 2018 Apr 27. Bioorg Med Chem. 2018. PMID: 29784271
Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus.
Klug DM, Tse EG, Silva DG, Cao Y, Charman SA, Chauhan J, Crighton E, Dichiara M, Drake C, Drewry D, da Silva Emery F, Ferrins L, Graves L, Hopkins E, Kresina TAC, Lorente-Macías Á, Perry B, Phipps R, Quiroga B, Quotadamo A, Sabatino GN, Sama A, Schätzlein A, Simpson QJ, Steele J, Shanu-Wilson J, Sjö P, Stapleton P, Swain CJ, Vaideanu A, Xie H, Zuercher W, Todd MH. Klug DM, et al. Among authors: stapleton p. ACS Infect Dis. 2023 Dec 8;9(12):2423-2435. doi: 10.1021/acsinfecdis.3c00286. Epub 2023 Nov 22. ACS Infect Dis. 2023. PMID: 37991879 Free PMC article.
310 results