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Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation.
Antioxid Redox Signal. 2014 Jun 10;20(17):2667-80. doi: 10.1089/ars.2013.5473. Epub 2014 Feb 3.
Antioxid Redox Signal. 2014.
PMID: 24206143
Free PMC article.
5-lipoxygenase: underappreciated role of a pro-inflammatory enzyme in tumorigenesis.
Steinhilber D, Fischer AS, Metzner J, Steinbrink SD, Roos J, Ruthardt M, Maier TJ.
Steinhilber D, et al. Among authors: steinbrink sd.
Front Pharmacol. 2010 Dec 24;1:143. doi: 10.3389/fphar.2010.00143. eCollection 2010.
Front Pharmacol. 2010.
PMID: 21833182
Free PMC article.
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5-Lipoxygenase inhibitors induce potent anti-proliferative and cytotoxic effects in human tumour cells independently of suppression of 5-lipoxygenase activity.
Fischer AS, Metzner J, Steinbrink SD, Ulrich S, Angioni C, Geisslinger G, Steinhilber D, Maier TJ.
Fischer AS, et al. Among authors: steinbrink sd.
Br J Pharmacol. 2010 Oct;161(4):936-49. doi: 10.1111/j.1476-5381.2010.00915.x.
Br J Pharmacol. 2010.
PMID: 20860670
Free PMC article.
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Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations.
Steinbrink SD, Pergola C, Bühring U, George S, Metzner J, Fischer AS, Häfner AK, Wisniewska JM, Geisslinger G, Werz O, Steinhilber D, Maier TJ.
Steinbrink SD, et al.
Cell Mol Life Sci. 2010 Mar;67(5):797-806. doi: 10.1007/s00018-009-0206-0. Epub 2009 Nov 29.
Cell Mol Life Sci. 2010.
PMID: 20091083
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Inhibitors of Human 5-Lipoxygenase Potently Interfere With Prostaglandin Transport.
Kahnt AS, Angioni C, Göbel T, Hofmann B, Roos J, Steinbrink SD, Rörsch F, Thomas D, Geisslinger G, Zacharowski K, Grösch S, Steinhilber D, Maier TJ.
Kahnt AS, et al. Among authors: steinbrink sd.
Front Pharmacol. 2022 Jan 21;12:782584. doi: 10.3389/fphar.2021.782584. eCollection 2021.
Front Pharmacol. 2022.
PMID: 35126121
Free PMC article.
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Cysteinyl leukotriene-receptor-1 antagonists interfere with PGE2 synthesis by inhibiting mPGES-1 activity.
Kahnt AS, Rörsch F, Diehl O, Hofmann B, Lehmann C, Steinbrink SD, Angioni C, Geisslinger G, Grösch S, Steinhilber D, Maier TJ.
Kahnt AS, et al. Among authors: steinbrink sd.
Biochem Pharmacol. 2013 Jul 15;86(2):286-96. doi: 10.1016/j.bcp.2013.05.005. Epub 2013 May 14.
Biochem Pharmacol. 2013.
PMID: 23684692
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