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Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.
Pewzner-Jung Y, Tavakoli Tabazavareh S, Grassmé H, Becker KA, Japtok L, Steinmann J, Joseph T, Lang S, Tuemmler B, Schuchman EH, Lentsch AB, Kleuser B, Edwards MJ, Futerman AH, Gulbins E. Pewzner-Jung Y, et al. Among authors: steinmann j. EMBO Mol Med. 2014 Sep;6(9):1205-14. doi: 10.15252/emmm.201404075. EMBO Mol Med. 2014. PMID: 25085879 Free PMC article.
Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice.
Henry BD, Neill DR, Becker KA, Gore S, Bricio-Moreno L, Ziobro R, Edwards MJ, Mühlemann K, Steinmann J, Kleuser B, Japtok L, Luginbühl M, Wolfmeier H, Scherag A, Gulbins E, Kadioglu A, Draeger A, Babiychuk EB. Henry BD, et al. Among authors: steinmann j. Nat Biotechnol. 2015 Jan;33(1):81-8. doi: 10.1038/nbt.3037. Epub 2014 Nov 2. Nat Biotechnol. 2015. PMID: 25362245
Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA.
Krüger A, Oldenburg M, Chebrolu C, Beisser D, Kolter J, Sigmund AM, Steinmann J, Schäfer S, Hochrein H, Rahmann S, Wagner H, Henneke P, Hornung V, Buer J, Kirschning CJ. Krüger A, et al. Among authors: steinmann j. EMBO Rep. 2015 Dec;16(12):1656-63. doi: 10.15252/embr.201540861. Epub 2015 Nov 6. EMBO Rep. 2015. PMID: 26545385 Free PMC article.
Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action.
Bongard J, Schmitz AL, Wolf A, Zischinsky G, Pieren M, Schellhorn B, Bravo-Rodriguez K, Schillinger J, Koch U, Nussbaumer P, Klebl B, Steinmann J, Buer J, Sanchez-Garcia E, Ehrmann M, Kaiser M. Bongard J, et al. Among authors: steinmann j. ChemMedChem. 2019 Jun 5;14(11):1074-1078. doi: 10.1002/cmdc.201900193. Epub 2019 Apr 24. ChemMedChem. 2019. PMID: 30945468
Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis.
Schäfer ST, Franken L, Adamzik M, Schumak B, Scherag A, Engler A, Schönborn N, Walden J, Koch S, Baba HA, Steinmann J, Westendorf AM, Fandrey J, Bieber T, Kurts C, Frede S, Peters J, Limmer A. Schäfer ST, et al. Among authors: steinmann j. Anesthesiology. 2016 Apr;124(4):923-33. doi: 10.1097/ALN.0000000000001008. Anesthesiology. 2016. PMID: 26808636 Free article.
The lung microbiome in patients with pneumocystosis.
Kehrmann J, Veckollari B, Schmidt D, Schildgen O, Schildgen V, Wagner N, Zeschnigk M, Klein-Hitpass L, Witzke O, Buer J, Steinmann J. Kehrmann J, et al. Among authors: steinmann j. BMC Pulm Med. 2017 Dec 4;17(1):170. doi: 10.1186/s12890-017-0512-5. BMC Pulm Med. 2017. PMID: 29202739 Free PMC article.
399 results