Stevers LM - Search Results

1

Rapid mapping of interactions between Human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy.

Sierecki E, Stevers LM, Giles N, Polinkovsky ME, Moustaqil M, Mureev S, Johnston WA, Dahmer-Heath M, Skalamera D, Gonda TJ, Gabrielli B, Collins BM, Alexandrov K, Gambin Y. Sierecki E, et al. Among authors: stevers lm. Mol Cell Proteomics. 2014 Sep;13(9):2233-45. doi: 10.1074/mcp.M113.037275. Epub 2014 May 27. Mol Cell Proteomics. 2014. PMID: 24866125 Free PMC article.

2

Small molecules, peptides and natural products: getting a grip on 14-3-3 protein-protein modulation.

Bartel M, Schäfer A, Stevers LM, Ottmann C. Bartel M, et al. Among authors: stevers lm. Future Med Chem. 2014 May;6(8):903-21. doi: 10.4155/fmc.14.47. Future Med Chem. 2014. PMID: 24962282 Review.

3

Modulators of 14-3-3 Protein-Protein Interactions.

Stevers LM, Sijbesma E, Botta M, MacKintosh C, Obsil T, Landrieu I, Cau Y, Wilson AJ, Karawajczyk A, Eickhoff J, Davis J, Hann M, O'Mahony G, Doveston RG, Brunsveld L, Ottmann C. Stevers LM, et al. J Med Chem. 2018 May 10;61(9):3755-3778. doi: 10.1021/acs.jmedchem.7b00574. Epub 2017 Oct 19. J Med Chem. 2018. PMID: 28968506 Free PMC article. Review.

4

Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.

Stevers LM, Lam CV, Leysen SF, Meijer FA, van Scheppingen DS, de Vries RM, Carlile GW, Milroy LG, Thomas DY, Brunsveld L, Ottmann C. Stevers LM, et al. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1152-61. doi: 10.1073/pnas.1516631113. Epub 2016 Feb 17. Proc Natl Acad Sci U S A. 2016. PMID: 26888287 Free PMC article.

5

Structural interface between LRRK2 and 14-3-3 protein.

Stevers LM, de Vries RM, Doveston RG, Milroy LG, Brunsveld L, Ottmann C. Stevers LM, et al. Biochem J. 2017 Mar 23;474(7):1273-1287. doi: 10.1042/BCJ20161078. Biochem J. 2017. PMID: 28202711

6

A Thermodynamic Model for Multivalency in 14-3-3 Protein-Protein Interactions.

Stevers LM, de Vink PJ, Ottmann C, Huskens J, Brunsveld L. Stevers LM, et al. J Am Chem Soc. 2018 Oct 31;140(43):14498-14510. doi: 10.1021/jacs.8b09618. Epub 2018 Oct 18. J Am Chem Soc. 2018. PMID: 30296824 Free PMC article.

7

Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.

Stevers LM, Wolter M, Carlile GW, Macdonald D, Richard L, Gielkens F, Hanrahan JW, Thomas DY, Chakka SK, Peterson ML, Thomas H, Brunsveld L, Ottmann C. Stevers LM, et al. Nat Commun. 2022 Jun 23;13(1):3586. doi: 10.1038/s41467-022-31206-6. Nat Commun. 2022. PMID: 35739107 Free PMC article.

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