Stewart EL - Search Results

1

X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain.

Biggadike K, Bledsoe RK, Hassell AM, Kirk BE, McLay IM, Shewchuk LM, Stewart EL. Biggadike K, et al. Among authors: stewart el. J Med Chem. 2008 Jun 26;51(12):3349-52. doi: 10.1021/jm800279t. Epub 2008 Jun 4. J Med Chem. 2008. PMID: 18522385

2

The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist.

Madauss KP, Bledsoe RK, Mclay I, Stewart EL, Uings IJ, Weingarten G, Williams SP. Madauss KP, et al. Among authors: stewart el. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6097-9. doi: 10.1016/j.bmcl.2008.10.021. Epub 2008 Oct 8. Bioorg Med Chem Lett. 2008. PMID: 18952422

3

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition.

Bledsoe RK, Montana VG, Stanley TB, Delves CJ, Apolito CJ, McKee DD, Consler TG, Parks DJ, Stewart EL, Willson TM, Lambert MH, Moore JT, Pearce KH, Xu HE. Bledsoe RK, et al. Among authors: stewart el. Cell. 2002 Jul 12;110(1):93-105. doi: 10.1016/s0092-8674(02)00817-6. Cell. 2002. PMID: 12151000 Free article.

4

Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.

Madauss KP, Deng SJ, Austin RJ, Lambert MH, McLay I, Pritchard J, Short SA, Stewart EL, Uings IJ, Williams SP. Madauss KP, et al. Among authors: stewart el. J Med Chem. 2004 Jun 17;47(13):3381-7. doi: 10.1021/jm030640n. J Med Chem. 2004. PMID: 15189034

5

Structure and function of the glucocorticoid receptor ligand binding domain.

Bledsoe RK, Stewart EL, Pearce KH. Bledsoe RK, et al. Among authors: stewart el. Vitam Horm. 2004;68:49-91. doi: 10.1016/S0083-6729(04)68002-2. Vitam Horm. 2004. PMID: 15193451 Review.

6

A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor.

Bledsoe RK, Madauss KP, Holt JA, Apolito CJ, Lambert MH, Pearce KH, Stanley TB, Stewart EL, Trump RP, Willson TM, Williams SP. Bledsoe RK, et al. Among authors: stewart el. J Biol Chem. 2005 Sep 2;280(35):31283-93. doi: 10.1074/jbc.M504098200. Epub 2005 Jun 20. J Biol Chem. 2005. PMID: 15967794 Free article.

7

The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.

Deaton DN, Do Y, Holt J, Jeune MR, Kramer HF, Larkin AL, Orband-Miller LA, Peckham GE, Poole C, Price DJ, Schaller LT, Shen Y, Shewchuk LM, Stewart EL, Stuart JD, Thomson SA, Ward P, Wilson JW, Xu T, Guss JH, Musetti C, Rendina AR, Affleck K, Anders D, Hancock AP, Hobbs H, Hodgson ST, Hutchinson J, Leveridge MV, Nicholls H, Smith IED, Somers DO, Sneddon HF, Uddin S, Cleasby A, Mortenson PN, Richardson C, Saxty G. Deaton DN, et al. Among authors: stewart el. Bioorg Med Chem. 2019 Apr 15;27(8):1456-1478. doi: 10.1016/j.bmc.2019.02.017. Epub 2019 Feb 11. Bioorg Med Chem. 2019. PMID: 30858025

8

The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure.

Cadilla R, Deaton DN, Do Y, Elkins PA, Ennulat D, Guss JH, Holt J, Jeune MR, King AG, Klapwijk JC, Kramer HF, Kramer NJ, Laffan SB, Masuria PI, McDougal AV, Mortenson PN, Musetti C, Peckham GE, Pietrak BL, Poole C, Price DJ, Rendina AR, Sati G, Saxty G, Shearer BG, Shewchuk LM, Sneddon HF, Stewart EL, Stuart JD, Thomas DN, Thomson SA, Ward P, Wilson JW, Xu T, Youngman MA. Cadilla R, et al. Among authors: stewart el. Bioorg Med Chem. 2020 Dec 1;28(23):115791. doi: 10.1016/j.bmc.2020.115791. Epub 2020 Oct 3. Bioorg Med Chem. 2020. PMID: 33059303

9

Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.

Becherer JD, Boros EE, Carpenter TY, Cowan DJ, Deaton DN, Haffner CD, Jeune MR, Kaldor IW, Poole JC, Preugschat F, Rheault TR, Schulte CA, Shearer BG, Shearer TW, Shewchuk LM, Smalley TL Jr, Stewart EL, Stuart JD, Ulrich JC. Becherer JD, et al. Among authors: stewart el. J Med Chem. 2015 Sep 10;58(17):7021-56. doi: 10.1021/acs.jmedchem.5b00992. Epub 2015 Aug 24. J Med Chem. 2015. PMID: 26267483

10

A pre-steady state and steady state kinetic analysis of the N-ribosyl hydrolase activity of hCD157.

Preugschat F, Carter LH, Boros EE, Porter DJ, Stewart EL, Shewchuk LM. Preugschat F, et al. Among authors: stewart el. Arch Biochem Biophys. 2014 Dec 15;564:156-63. doi: 10.1016/j.abb.2014.09.008. Epub 2014 Sep 20. Arch Biochem Biophys. 2014. PMID: 25250980

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

80 results

Search Page