Stirling D - Search Results

1

Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects.

Dredge K, Marriott JB, Macdonald CD, Man HW, Chen R, Muller GW, Stirling D, Dalgleish AG. Dredge K, et al. Among authors: stirling d. Br J Cancer. 2002 Nov 4;87(10):1166-72. doi: 10.1038/sj.bjc.6600607. Br J Cancer. 2002. PMID: 12402158 Free PMC article.

2

Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro.

Dredge K, Horsfall R, Robinson SP, Zhang LH, Lu L, Tang Y, Shirley MA, Muller G, Schafer P, Stirling D, Dalgleish AG, Bartlett JB. Dredge K, et al. Among authors: stirling d. Microvasc Res. 2005 Jan;69(1-2):56-63. doi: 10.1016/j.mvr.2005.01.002. Microvasc Res. 2005. PMID: 15797261

3

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells.

Galustian C, Meyer B, Labarthe MC, Dredge K, Klaschka D, Henry J, Todryk S, Chen R, Muller G, Stirling D, Schafer P, Bartlett JB, Dalgleish AG. Galustian C, et al. Among authors: stirling d. Cancer Immunol Immunother. 2009 Jul;58(7):1033-45. doi: 10.1007/s00262-008-0620-4. Epub 2008 Nov 14. Cancer Immunol Immunother. 2009. PMID: 19009291 Free PMC article.

4

A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins.

Marriott JB, Clarke IA, Czajka A, Dredge K, Childs K, Man HW, Schafer P, Govinda S, Muller GW, Stirling DI, Dalgleish AG. Marriott JB, et al. Cancer Res. 2003 Feb 1;63(3):593-9. Cancer Res. 2003. PMID: 12566301

5

CC-3052: a water-soluble analog of thalidomide and potent inhibitor of activation-induced TNF-alpha production.

Marriott JB, Westby M, Cookson S, Guckian M, Goodbourn S, Muller G, Shire MG, Stirling D, Dalgleish AG. Marriott JB, et al. Among authors: stirling d. J Immunol. 1998 Oct 15;161(8):4236-43. J Immunol. 1998. PMID: 9780198

6

Immunotherapeutic and antitumour potential of thalidomide analogues.

Marriott JB, Muller G, Stirling D, Dalgleish AG. Marriott JB, et al. Among authors: stirling d. Expert Opin Biol Ther. 2001 Jul;1(4):675-82. doi: 10.1517/14712598.1.4.675. Expert Opin Biol Ther. 2001. PMID: 11727503 Review.

7

Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells.

Marriott JB, Clarke IA, Dredge K, Muller G, Stirling D, Dalgleish AG. Marriott JB, et al. Among authors: stirling d. Clin Exp Immunol. 2002 Oct;130(1):75-84. doi: 10.1046/j.1365-2249.2002.01954.x. Clin Exp Immunol. 2002. PMID: 12296856 Free PMC article. Clinical Trial.

8

Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers.

Bartlett JB, Michael A, Clarke IA, Dredge K, Nicholson S, Kristeleit H, Polychronis A, Pandha H, Muller GW, Stirling DI, Zeldis J, Dalgleish AG. Bartlett JB, et al. Among authors: stirling di. Br J Cancer. 2004 Mar 8;90(5):955-61. doi: 10.1038/sj.bjc.6601579. Br J Cancer. 2004. PMID: 14997189 Free PMC article. Clinical Trial.

9

Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells.

Mouratidis PX, Colston KW, Bartlett JB, Muller GW, Man HW, Stirling D, Dalgleish AG. Mouratidis PX, et al. Among authors: stirling d. Pancreas. 2009 Jan;38(1):78-84. doi: 10.1097/mpa.0b013e318183d72f. Pancreas. 2009. PMID: 19117086

10

Alpha-fluoro-substituted thalidomide analogues.

Man HW, Corral LG, Stirling DI, Muller GW. Man HW, et al. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3415-7. doi: 10.1016/s0960-894x(03)00778-9. Bioorg Med Chem Lett. 2003. PMID: 14505639

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