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Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase.
Pauwels R, Andries K, Debyser Z, Van Daele P, Schols D, Stoffels P, De Vreese K, Woestenborghs R, Vandamme AM, Janssen CG, et al. Pauwels R, et al. Among authors: stoffels p. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1711-5. doi: 10.1073/pnas.90.5.1711. Proc Natl Acad Sci U S A. 1993. PMID: 7680476 Free PMC article.
Characterization of HIV-1 strains isolated from patients treated with TIBO R82913.
Vandamme AM, Debyser Z, Pauwels R, De Vreese K, Goubau P, Youle M, Gazzard B, Stoffels PA, Cauwenbergh GF, Anne J, et al. Vandamme AM, et al. Among authors: stoffels pa. AIDS Res Hum Retroviruses. 1994 Jan;10(1):39-46. doi: 10.1089/aid.1994.10.39. AIDS Res Hum Retroviruses. 1994. PMID: 7514016
Patterns of resistance and cross-resistance to human immunodeficiency virus type 1 reverse transcriptase inhibitors in patients treated with the nonnucleoside reverse transcriptase inhibitor loviride.
Miller V, de Béthune MP, Kober A, Stürmer M, Hertogs K, Pauwels R, Stoffels P, Staszewski S. Miller V, et al. Among authors: stoffels p. Antimicrob Agents Chemother. 1998 Dec;42(12):3123-9. doi: 10.1128/AAC.42.12.3123. Antimicrob Agents Chemother. 1998. PMID: 9835502 Free PMC article. Clinical Trial.
Virological and immunological analysis of a triple combination pilot study with loviride, lamivudine and zidovudine in HIV-1-infected patients.
Staszewski S, Miller V, Rehmet S, Stark T, De Crée J, De Brabander M, Peeters M, Andries K, Moeremans M, De Raeymaeker M, Pearce G, Van den Broeck R, Verbiest W, Stoffels P. Staszewski S, et al. Among authors: stoffels p. AIDS. 1996 May;10(5):F1-7. doi: 10.1097/00002030-199605000-00001. AIDS. 1996. PMID: 8724034 Clinical Trial.
Evaluation of the efficacy and tolerance of R 018893, R 089439 (loviride) and placebo in asymptomatic HIV-1-infected patients. Loviride Collaborative Study Group.
Staszewski S, Miller V, Kober A, Colebunders R, Vandercam B, Delescluse J, Clumeck N, Van Wanzeele F, De Brabander M, De Creé J, Moeremans M, Andries K, Boucher C, Stoffels P, Janssen PA. Staszewski S, et al. Among authors: stoffels p. Antivir Ther. 1996 Jan;1(1):42-50. Antivir Ther. 1996. PMID: 11322258 Clinical Trial. No abstract available.
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).
Janssen PA, Lewi PJ, Arnold E, Daeyaert F, de Jonge M, Heeres J, Koymans L, Vinkers M, Guillemont J, Pasquier E, Kukla M, Ludovici D, Andries K, de Béthune MP, Pauwels R, Das K, Clark AD Jr, Frenkel YV, Hughes SH, Medaer B, De Knaep F, Bohets H, De Clerck F, Lampo A, Williams P, Stoffels P. Janssen PA, et al. Among authors: stoffels p. J Med Chem. 2005 Mar 24;48(6):1901-9. doi: 10.1021/jm040840e. J Med Chem. 2005. PMID: 15771434 Review.
Diclazuril for Isospora belli infection in AIDS.
Kayembe K, Desmet P, Henry MC, Stoffels P. Kayembe K, et al. Among authors: stoffels p. Lancet. 1989 Jun 17;1(8651):1397-8. doi: 10.1016/s0140-6736(89)92853-5. Lancet. 1989. PMID: 2567420 No abstract available.
25 results