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Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.
Harrison JS, Cornett EM, Goldfarb D, DaRosa PA, Li ZM, Yan F, Dickson BM, Guo AH, Cantu DV, Kaustov L, Brown PJ, Arrowsmith CH, Erie DA, Major MB, Klevit RE, Krajewski K, Kuhlman B, Strahl BD, Rothbart SB. Harrison JS, et al. Among authors: strahl bd. Elife. 2016 Sep 6;5:e17101. doi: 10.7554/eLife.17101. Elife. 2016. PMID: 27595565 Free PMC article.
Peptide microarrays to interrogate the "histone code".
Rothbart SB, Krajewski K, Strahl BD, Fuchs SM. Rothbart SB, et al. Among authors: strahl bd. Methods Enzymol. 2012;512:107-35. doi: 10.1016/B978-0-12-391940-3.00006-8. Methods Enzymol. 2012. PMID: 22910205 Free PMC article.
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.
Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD. Rothbart SB, et al. Among authors: strahl bd. Nat Struct Mol Biol. 2012 Nov;19(11):1155-60. doi: 10.1038/nsmb.2391. Epub 2012 Sep 30. Nat Struct Mol Biol. 2012. PMID: 23022729 Free PMC article.
186 results