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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids.
Bowles KR, Silva MC, Whitney K, Bertucci T, Berlind JE, Lai JD, Garza JC, Boles NC, Mahali S, Strang KH, Marsh JA, Chen C, Pugh DA, Liu Y, Gordon RE, Goderie SK, Chowdhury R, Lotz S, Lane K, Crary JF, Haggarty SJ, Karch CM, Ichida JK, Goate AM, Temple S. Bowles KR, et al. Among authors: strang kh. Cell. 2021 Aug 19;184(17):4547-4563.e17. doi: 10.1016/j.cell.2021.07.003. Epub 2021 Jul 26. Cell. 2021. PMID: 34314701 Free PMC article.
Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.
Koller EJ, Gonzalez De La Cruz E, Machula T, Ibanez KR, Lin WL, Williams T, Riffe CJ, Ryu D, Strang KH, Liu X, Janus C, Golde TE, Dickson D, Giasson BI, Chakrabarty P. Koller EJ, et al. Among authors: strang kh. Hum Mol Genet. 2019 Oct 1;28(19):3255-3269. doi: 10.1093/hmg/ddz151. Hum Mol Genet. 2019. PMID: 31261380 Free PMC article.
Phosphorylation of serine 305 in tau inhibits aggregation.
Strang KH, Sorrentino ZA, Riffe CJ, Gorion KM, Vijayaraghavan N, Golde TE, Giasson BI. Strang KH, et al. Neurosci Lett. 2019 Jan 23;692:187-192. doi: 10.1016/j.neulet.2018.11.011. Epub 2018 Nov 10. Neurosci Lett. 2019. PMID: 30423399 Free PMC article.
34 results