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PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development.
Drelon C, Berthon A, Sahut-Barnola I, Mathieu M, Dumontet T, Rodriguez S, Batisse-Lignier M, Tabbal H, Tauveron I, Lefrançois-Martinez AM, Pointud JC, Gomez-Sanchez CE, Vainio S, Shan J, Sacco S, Schedl A, Stratakis CA, Martinez A, Val P. Drelon C, et al. Among authors: stratakis ca. Nat Commun. 2016 Sep 14;7:12751. doi: 10.1038/ncomms12751. Nat Commun. 2016. PMID: 27624192 Free PMC article.
Mouse model for bilateral adrenal hyperplasia.
Sahut-Barnola I, De Joussineau C, Val P, Lambert-Langlais S, Lefrançois-Martinez AM, Pointud JC, Marceau G, Sapin V, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A. Sahut-Barnola I, et al. Among authors: stratakis ca. Ann Endocrinol (Paris). 2009 Jun;70(3):194. doi: 10.1016/j.ando.2009.02.004. Epub 2009 Mar 14. Ann Endocrinol (Paris). 2009. PMID: 19286161 Free PMC article. No abstract available.
Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.
Sahut-Barnola I, de Joussineau C, Val P, Lambert-Langlais S, Damon C, Lefrançois-Martinez AM, Pointud JC, Marceau G, Sapin V, Tissier F, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A. Sahut-Barnola I, et al. Among authors: stratakis ca. PLoS Genet. 2010 Jun 10;6(6):e1000980. doi: 10.1371/journal.pgen.1000980. PLoS Genet. 2010. PMID: 20548949 Free PMC article.
The cAMP pathway and the control of adrenocortical development and growth.
de Joussineau C, Sahut-Barnola I, Levy I, Saloustros E, Val P, Stratakis CA, Martinez A. de Joussineau C, et al. Among authors: stratakis ca. Mol Cell Endocrinol. 2012 Mar 31;351(1):28-36. doi: 10.1016/j.mce.2011.10.006. Epub 2011 Oct 15. Mol Cell Endocrinol. 2012. PMID: 22019902 Free PMC article. Review.
mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).
de Joussineau C, Sahut-Barnola I, Tissier F, Dumontet T, Drelon C, Batisse-Lignier M, Tauveron I, Pointud JC, Lefrançois-Martinez AM, Stratakis CA, Bertherat J, Val P, Martinez A. de Joussineau C, et al. Among authors: stratakis ca. Hum Mol Genet. 2014 Oct 15;23(20):5418-28. doi: 10.1093/hmg/ddu265. Epub 2014 May 27. Hum Mol Genet. 2014. PMID: 24865460 Free PMC article.
763 results