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Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.
Ananthanarayanan M, Li Y, Surapureddi S, Balasubramaniyan N, Ahn J, Goldstein JA, Suchy FJ. Ananthanarayanan M, et al. Among authors: suchy fj. Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G771-81. doi: 10.1152/ajpgi.00499.2010. Epub 2011 Feb 17. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21330447 Free PMC article.
Bile salt excretory pump: biology and pathobiology.
Suchy FJ, Ananthanarayanan M. Suchy FJ, et al. J Pediatr Gastroenterol Nutr. 2006 Jul;43 Suppl 1:S10-6. doi: 10.1097/01.mpg.0000226385.71859.5f. J Pediatr Gastroenterol Nutr. 2006. PMID: 16819395 Review.
Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene.
Geier A, Martin IV, Dietrich CG, Balasubramaniyan N, Strauch S, Suchy FJ, Gartung C, Trautwein C, Ananthanarayanan M. Geier A, et al. Among authors: suchy fj. Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G226-33. doi: 10.1152/ajpgi.00012.2008. Epub 2008 May 15. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18483185 Free PMC article.
147 results