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Omentum is better site than kidney capsule for growth, differentiation, and vascularization of immature porcine β-cell implants in immunodeficient rats.
Bartholomeus K, Jacobs-Tulleneers-Thevissen D, Shouyue S, Suenens K, In't Veld PA, Pipeleers-Marichal M, Pipeleers DG, Hellemans K. Bartholomeus K, et al. Among authors: suenens k. Transplantation. 2013 Dec 27;96(12):1026-33. doi: 10.1097/TP.0b013e3182a6ee41. Transplantation. 2013. PMID: 24056625 Free PMC article.
Human islet cell implants in a nude rat model of diabetes survive better in omentum than in liver with a positive influence of beta cell number and purity.
Jacobs-Tulleneers-Thevissen D, Bartholomeus K, Suenens K, Vermeulen I, Ling Z, Hellemans KH, In't Veld P, Pipeleers-Marichal M, Pipeleers D. Jacobs-Tulleneers-Thevissen D, et al. Among authors: suenens k. Diabetologia. 2010 Aug;53(8):1690-9. doi: 10.1007/s00125-010-1721-0. Epub 2010 Apr 16. Diabetologia. 2010. PMID: 20397000
Reversal of hyperglycemia in diabetic mice by a marginal islet mass together with human blood outgrowth endothelial cells is independent of the delivery technique and blood clot-induced processes.
Coppens V, Heremans Y, Leuckx G, Suenens K, Jacobs-Tulleneers-Thevissen D, Verdonck K, Luttun A, Heimberg H, De Leu N. Coppens V, et al. Among authors: suenens k. Islets. 2013 Sep-Dec;5(5):196-200. doi: 10.4161/isl.26778. Epub 2013 Nov 8. Islets. 2013. PMID: 24213480 Free PMC article.
Composition and function of macroencapsulated human embryonic stem cell-derived implants: comparison with clinical human islet cell grafts.
Motté E, Szepessy E, Suenens K, Stangé G, Bomans M, Jacobs-Tulleneers-Thevissen D, Ling Z, Kroon E, Pipeleers D; Beta Cell Therapy Consortium EU-FP7. Motté E, et al. Among authors: suenens k. Am J Physiol Endocrinol Metab. 2014 Nov 1;307(9):E838-46. doi: 10.1152/ajpendo.00219.2014. Epub 2014 Sep 9. Am J Physiol Endocrinol Metab. 2014. PMID: 25205822 Free article.
Cell Mass Increase Associated with Formation of Glucose-Controlling β-Cell Mass in Device-Encapsulated Implants of hiPS-Derived Pancreatic Endoderm.
Robert T, De Mesmaeker I, Van Hulle FO, Suenens KG, Stangé GM, Ling Z, Haller C, Bouche N, Keymeulen B, Kraus MRC, Pipeleers DG. Robert T, et al. Among authors: suenens kg. Stem Cells Transl Med. 2019 Dec;8(12):1296-1305. doi: 10.1002/sctm.19-0043. Epub 2019 Aug 4. Stem Cells Transl Med. 2019. PMID: 31379140 Free PMC article.
Formation of amyloid in encapsulated human pancreatic and human stem cell-generated beta cell implants.
Van Hulle F, De Groot K, Stangé G, Suenens K, De Mesmaeker I, De Paep DL, Ling Z, Hilbrands R, Gillard P, Keymeulen B, Kroon E, Westermark GT, Jacobs-Tulleneers-Thevissen D, Pipeleers D. Van Hulle F, et al. Among authors: suenens k. Am J Transplant. 2021 Jun;21(6):2090-2099. doi: 10.1111/ajt.16398. Epub 2020 Dec 6. Am J Transplant. 2021. PMID: 33206461 Free article.
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