Sun H - Search Results

1

Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K⁺ channel.

Nematian-Ardestani E, Abd-Wahab F, Chatelain FC, Sun H, Schewe M, Baukrowitz T, Tucker SJ. Nematian-Ardestani E, et al. Among authors: sun h. J Biol Chem. 2020 Jan 10;295(2):610-618. doi: 10.1074/jbc.RA119.010612. Epub 2019 Dec 5. J Biol Chem. 2020. PMID: 31806709 Free PMC article.

2

A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.

Schewe M, Nematian-Ardestani E, Sun H, Musinszki M, Cordeiro S, Bucci G, de Groot BL, Tucker SJ, Rapedius M, Baukrowitz T. Schewe M, et al. Among authors: sun h. Cell. 2016 Feb 25;164(5):937-49. doi: 10.1016/j.cell.2016.02.002. Cell. 2016. PMID: 26919430 Free PMC article.

3

A pharmacological master key mechanism that unlocks the selectivity filter gate in K⁺ channels.

Schewe M, Sun H, Mert Ü, Mackenzie A, Pike ACW, Schulz F, Constantin C, Vowinkel KS, Conrad LJ, Kiper AK, Gonzalez W, Musinszki M, Tegtmeier M, Pryde DC, Belabed H, Nazare M, de Groot BL, Decher N, Fakler B, Carpenter EP, Tucker SJ, Baukrowitz T. Schewe M, et al. Among authors: sun h. Science. 2019 Feb 22;363(6429):875-880. doi: 10.1126/science.aav0569. Science. 2019. PMID: 30792303 Free PMC article.

4

The conduction pathway of potassium channels is water free under physiological conditions.

Öster C, Hendriks K, Kopec W, Chevelkov V, Shi C, Michl D, Lange S, Sun H, de Groot BL, Lange A. Öster C, et al. Among authors: sun h. Sci Adv. 2019 Jul 31;5(7):eaaw6756. doi: 10.1126/sciadv.aaw6756. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31392272 Free PMC article.

5

Sodium Ions Do Not Stabilize the Selectivity Filter of a Potassium Channel.

Hendriks K, Öster C, Shi C, Sun H, Lange A. Hendriks K, et al. Among authors: sun h. J Mol Biol. 2021 Jul 23;433(15):167091. doi: 10.1016/j.jmb.2021.167091. Epub 2021 Jun 4. J Mol Biol. 2021. PMID: 34090923

6

A single NaK channel conformation is not enough for non-selective ion conduction.

Shi C, He Y, Hendriks K, de Groot BL, Cai X, Tian C, Lange A, Sun H. Shi C, et al. Among authors: sun h. Nat Commun. 2018 Feb 19;9(1):717. doi: 10.1038/s41467-018-03179-y. Nat Commun. 2018. PMID: 29459730 Free PMC article.

7

Nonselective cation permeation in an AMPA-type glutamate receptor.

Biedermann J, Braunbeck S, Plested AJR, Sun H. Biedermann J, et al. Among authors: sun h. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2012843118. doi: 10.1073/pnas.2012843118. Proc Natl Acad Sci U S A. 2021. PMID: 33602810 Free PMC article.

8

Structural plasticity of the selectivity filter in a nonselective ion channel.

Roy RN, Hendriks K, Kopec W, Abdolvand S, Weiss KL, de Groot BL, Lange A, Sun H, Coates L. Roy RN, et al. Among authors: sun h. IUCrJ. 2021 Apr 2;8(Pt 3):421-430. doi: 10.1107/S205225252100213X. eCollection 2021 May 1. IUCrJ. 2021. PMID: 33953928 Free PMC article.

9

Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors.

Minniberger S, Abdolvand S, Braunbeck S, Sun H, Plested AJR. Minniberger S, et al. Among authors: sun h. J Mol Biol. 2023 Mar 15;435(6):167970. doi: 10.1016/j.jmb.2023.167970. Epub 2023 Jan 20. J Mol Biol. 2023. PMID: 36682679

10

Deciphering the Multisite Interactions of a Protein and Its Ligand at Atomic Resolution by Using Sensitive Paramagnetic Effects.

Ma FH, Wang X, Chen JL, Wen X, Sun H, Su XC. Ma FH, et al. Among authors: sun h. Chemistry. 2017 Jan 18;23(4):926-934. doi: 10.1002/chem.201604393. Epub 2016 Dec 14. Chemistry. 2017. PMID: 27809357

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