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Chemical Proteomics with Novel Fully Functionalized Fragments and Stringent Target Prioritization Identifies the Glutathione-Dependent Isomerase GSTZ1 as a Lung Cancer Target.
Liao Y, Chin Chan S, Welsh EA, Fang B, Sun L, Schönbrunn E, Koomen JM, Duckett DR, Haura EB, Monastyrskyi A, Rix U. Liao Y, et al. Among authors: sun l. ACS Chem Biol. 2023 Feb 17;18(2):251-264. doi: 10.1021/acschembio.2c00587. Epub 2023 Jan 11. ACS Chem Biol. 2023. PMID: 36630201
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice.
Faber EB, Wang N, John K, Sun L, Wong HL, Burban D, Francis R, Tian D, Hong KH, Yang A, Wang L, Elsaid M, Khalid H, Levinson NM, Schönbrunn E, Hawkinson JE, Georg GI. Faber EB, et al. Among authors: sun l. J Med Chem. 2023 Feb 9;66(3):1928-1940. doi: 10.1021/acs.jmedchem.2c01731. Epub 2023 Jan 26. J Med Chem. 2023. PMID: 36701569
Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Faber EB, Sun L, Tang J, Roberts E, Ganeshkumar S, Wang N, Rasmussen D, Majumdar A, Hirsch LE, John K, Yang A, Khalid H, Hawkinson JE, Levinson NM, Chennathukuzhi V, Harki DA, Schönbrunn E, Georg GI. Faber EB, et al. Among authors: sun l. Nat Commun. 2023 Jun 3;14(1):3213. doi: 10.1038/s41467-023-38732-x. Nat Commun. 2023. PMID: 37270540 Free PMC article.
Thymocyte migration and emigration.
Tong Q, Yao L, Su M, Yang YG, Sun L. Tong Q, et al. Among authors: sun l. Immunol Lett. 2024 Apr 30:106861. doi: 10.1016/j.imlet.2024.106861. Online ahead of print. Immunol Lett. 2024. PMID: 38697225
29,662 results
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