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A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.
Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Febbraio M, Hajjar DP, Silverstein RL, Hoff HF, Salomon RG, Hazen SL. Podrez EA, et al. Among authors: sun m. J Biol Chem. 2002 Oct 11;277(41):38517-23. doi: 10.1074/jbc.M205924200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145296 Free article.
In a companion article we reported the characterization of a structurally conserved family of oxidized choline glycerophospholipids (oxPC(CD36)) that serve as novel high affinity ligands for cells stably transfected with CD36, mediating recognition of multiple oxidized forms of L …
In a companion article we reported the characterization of a structurally conserved family of oxidized choline glycerophospholipids (oxPC(CD …
Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.
Sun M, Finnemann SC, Febbraio M, Shan L, Annangudi SP, Podrez EA, Hoppe G, Darrow R, Organisciak DT, Salomon RG, Silverstein RL, Hazen SL. Sun M, et al. J Biol Chem. 2006 Feb 17;281(7):4222-30. doi: 10.1074/jbc.M509769200. Epub 2005 Dec 13. J Biol Chem. 2006. PMID: 16354659 Free PMC article.
Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.
Podrez EA, Byzova TV, Febbraio M, Salomon RG, Ma Y, Valiyaveettil M, Poliakov E, Sun M, Finton PJ, Curtis BR, Chen J, Zhang R, Silverstein RL, Hazen SL. Podrez EA, et al. Among authors: sun m. Nat Med. 2007 Sep;13(9):1086-95. doi: 10.1038/nm1626. Epub 2007 Aug 26. Nat Med. 2007. PMID: 17721545 Free PMC article.
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