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The purification and characterization of the catalytic domain of Src expressed in Schizosaccharomyces pombe. Comparison of unphosphorylated and tyrosine phosphorylated species.
Weijland A, Neubauer G, Courtneidge SA, Mann M, Wierenga RK, Superti-Furga G. Weijland A, et al. Eur J Biochem. 1996 Sep 15;240(3):756-64. doi: 10.1111/j.1432-1033.1996.0756h.x. Eur J Biochem. 1996. PMID: 8856081
Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity.
Lorenz S, Deng P, Hantschel O, Superti-Furga G, Kuriyan J. Lorenz S, et al. Biochem J. 2015 Jun 1;468(2):283-91. doi: 10.1042/BJ20141492. Biochem J. 2015. PMID: 25779001 Free PMC article.
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.
Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J. Nagar B, et al. Mol Cell. 2006 Mar 17;21(6):787-98. doi: 10.1016/j.molcel.2006.01.035. Mol Cell. 2006. PMID: 16543148
High-affinity Src-SH2 ligands which do not activate Tyr(527)-phosphorylated Src in an experimental in vivo system.
Mandine E, Jean-Baptiste V, Vayssière B, Gofflo D, Bénard D, Sarubbi E, Deprez P, Baron R, Superti-Furga G, Lesuisse D. Mandine E, et al. Biochem Biophys Res Commun. 2002 Oct 25;298(2):185-92. doi: 10.1016/s0006-291x(02)02424-5. Biochem Biophys Res Commun. 2002. PMID: 12387813
c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs.
Ostareck-Lederer A, Ostareck DH, Cans C, Neubauer G, Bomsztyk K, Superti-Furga G, Hentze MW. Ostareck-Lederer A, et al. Mol Cell Biol. 2002 Jul;22(13):4535-43. doi: 10.1128/mcb.22.13.4535-4543.2002. Mol Cell Biol. 2002. PMID: 12052863 Free PMC article.
Regulation of c-Fes tyrosine kinase activity by coiled-coil and SH2 domains: analysis with Saccharomyces cerevisiae.
Takashima Y, Delfino FJ, Engen JR, Superti-Furga G, Smithgall TE. Takashima Y, et al. Biochemistry. 2003 Apr 1;42(12):3567-74. doi: 10.1021/bi0272499. Biochemistry. 2003. PMID: 12653561
A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.
Wojcik J, Hantschel O, Grebien F, Kaupe I, Bennett KL, Barkinge J, Jones RB, Koide A, Superti-Furga G, Koide S. Wojcik J, et al. Nat Struct Mol Biol. 2010 Apr;17(4):519-27. doi: 10.1038/nsmb.1793. Epub 2010 Mar 28. Nat Struct Mol Biol. 2010. PMID: 20357770 Free PMC article.
Regulation of the c-Abl and Bcr-Abl tyrosine kinases.
Hantschel O, Superti-Furga G. Hantschel O, et al. Nat Rev Mol Cell Biol. 2004 Jan;5(1):33-44. doi: 10.1038/nrm1280. Nat Rev Mol Cell Biol. 2004. PMID: 14708008 Review.
Structural basis for the autoinhibition of c-Abl tyrosine kinase.
Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Nagar B, et al. Cell. 2003 Mar 21;112(6):859-71. doi: 10.1016/s0092-8674(03)00194-6. Cell. 2003. PMID: 12654251
A myristoyl/phosphotyrosine switch regulates c-Abl.
Hantschel O, Nagar B, Guettler S, Kretzschmar J, Dorey K, Kuriyan J, Superti-Furga G. Hantschel O, et al. Cell. 2003 Mar 21;112(6):845-57. doi: 10.1016/s0092-8674(03)00191-0. Cell. 2003. PMID: 12654250
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