Suri V - Search Results

1

beta-Keto sulfones as inhibitors of 11beta-hydroxysteroid dehydrogenase type I and the mechanism of action.

Xiang J, Ipek M, Suri V, Tam M, Xing Y, Huang N, Zhang Y, Tobin J, Mansour TS, McKew J. Xiang J, et al. Among authors: suri v. Bioorg Med Chem. 2007 Jul 1;15(13):4396-405. doi: 10.1016/j.bmc.2007.04.035. Epub 2007 Apr 25. Bioorg Med Chem. 2007. PMID: 17490884

2

Synthesis and biological evaluation of sulfonamidooxazoles and beta-keto sulfones: selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.

Xiang J, Ipek M, Suri V, Massefski W, Pan N, Ge Y, Tam M, Xing Y, Tobin JF, Xu X, Tam S. Xiang J, et al. Among authors: suri v. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2865-9. doi: 10.1016/j.bmcl.2005.03.093. Bioorg Med Chem Lett. 2005. PMID: 15911270

3

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.

Xiang J, Wan ZK, Li HQ, Ipek M, Binnun E, Nunez J, Chen L, McKew JC, Mansour TS, Xu X, Suri V, Tam M, Xing Y, Li X, Hahm S, Tobin J, Saiah E. Xiang J, et al. Among authors: suri v. J Med Chem. 2008 Jul 24;51(14):4068-71. doi: 10.1021/jm8004948. Epub 2008 Jun 26. J Med Chem. 2008. PMID: 18578516

4

Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.

Wan ZK, Chenail E, Xiang J, Li HQ, Ipek M, Bard J, Svenson K, Mansour TS, Xu X, Tian X, Suri V, Hahm S, Xing Y, Johnson CE, Li X, Qadri A, Panza D, Perreault M, Tobin JF, Saiah E. Wan ZK, et al. Among authors: suri v. J Med Chem. 2009 Sep 10;52(17):5449-61. doi: 10.1021/jm900639u. J Med Chem. 2009. PMID: 19673466

5

Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes.

Wan ZK, Chenail E, Li HQ, Ipek M, Xiang J, Suri V, Hahm S, Bard J, Svenson K, Xu X, Tian X, Wang M, Li X, Johnson CE, Qadri A, Panza D, Perreault M, Mansour TS, Tobin JF, Saiah E. Wan ZK, et al. Among authors: suri v. ACS Med Chem Lett. 2012 Nov 23;4(1):118-23. doi: 10.1021/ml300352x. eCollection 2013 Jan 10. ACS Med Chem Lett. 2012. PMID: 24900572 Free PMC article.

6

H6PDH interacts directly with 11beta-HSD1: implications for determining the directionality of glucocorticoid catalysis.

Zhang YL, Zhong X, Gjoka Z, Li Y, Stochaj W, Stahl M, Kriz R, Tobin JF, Erbe D, Suri V. Zhang YL, et al. Among authors: suri v. Arch Biochem Biophys. 2009 Mar 1;483(1):45-54. doi: 10.1016/j.abb.2008.12.004. Epub 2008 Dec 24. Arch Biochem Biophys. 2009. PMID: 19121282

7

Targeting Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases.

Cao J, Zhou Y, Peng H, Huang X, Stahler S, Suri V, Qadri A, Gareski T, Jones J, Hahm S, Perreault M, McKew J, Shi M, Xu X, Tobin JF, Gimeno RE. Cao J, et al. Among authors: suri v. J Biol Chem. 2011 Dec 2;286(48):41838-41851. doi: 10.1074/jbc.M111.245456. Epub 2011 Oct 11. J Biol Chem. 2011. PMID: 21990351 Free PMC article.

8

Comparative pharmacokinetics and metabolism studies in lean and diet- induced obese mice: an animal efficacy model for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors.

Wang M, Tian X, Leung L, Wang J, Houvig N, Xiang J, Wan ZK, Saiah E, Hahm S, Suri V, Xu X. Wang M, et al. Among authors: suri v. Drug Metab Lett. 2011 Jan;5(1):55-63. doi: 10.2174/187231211794455280. Drug Metab Lett. 2011. PMID: 21198436

9

Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists.

Erbe DV, Gartrell K, Zhang YL, Suri V, Kirincich SJ, Will S, Perreault M, Wang S, Tobin JF. Erbe DV, et al. Among authors: suri v. Vascul Pharmacol. 2006 Sep;45(3):154-62. doi: 10.1016/j.vph.2006.05.002. Epub 2006 May 16. Vascul Pharmacol. 2006. PMID: 16765099

10

Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.

Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Hsin-Jung Li S, Friedman A, Manfredi MG, Gitai Z, Kim H, Rabinowitz JD. Ducker GS, et al. Among authors: suri v. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11404-11409. doi: 10.1073/pnas.1706617114. Epub 2017 Oct 9. Proc Natl Acad Sci U S A. 2017. PMID: 29073064 Free PMC article.

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