Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response.
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Nat Commun. 2019 Jan 3;10(1):38. doi: 10.1038/s41467-018-07841-3.
Nat Commun. 2019.
PMID: 30604764
Free PMC article.
A subset of severity genes improves prediction of corticosteroid-induced remission in the discovery cohort; this gene signature is also associated with response to anti-TNFalpha and anti-alpha(4)beta(7) integrin in adults. The severity and therapeutic response gene …
A subset of severity genes improves prediction of corticosteroid-induced remission in the discovery cohort; this gene signature is also asso …