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Autoregulation of thyroid-specific gene transcription by thyroglobulin.
Suzuki K, Lavaroni S, Mori A, Ohta M, Saito J, Pietrarelli M, Singer DS, Kimura S, Katoh R, Kawaoi A, Kohn LD. Suzuki K, et al. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8251-6. doi: 10.1073/pnas.95.14.8251. Proc Natl Acad Sci U S A. 1998. PMID: 9653173 Free PMC article.
Follicular thyroglobulin (TG) suppression of thyroid-restricted genes involves the apical membrane asialoglycoprotein receptor and TG phosphorylation.
Ulianich L, Suzuki K, Mori A, Nakazato M, Pietrarelli M, Goldsmith P, Pacifico F, Consiglio E, Formisano S, Kohn LD. Ulianich L, et al. Among authors: suzuki k. J Biol Chem. 1999 Aug 27;274(35):25099-107. doi: 10.1074/jbc.274.35.25099. J Biol Chem. 1999. PMID: 10455190 Free article.
Follicular thyroglobulin (TG) decreases expression of the thyroid-restricted transcription factors, thyroid transcription factor (TTF)-1, TTF-2, and Pax-8, thereby suppressing expression of the sodium iodide symporter, thyroid peroxidase, TG, and thyrotropin receptor genes (Su
Follicular thyroglobulin (TG) decreases expression of the thyroid-restricted transcription factors, thyroid transcription factor (TTF)-1, TT …
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