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The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).
Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, Xavier RJ, Urrutia RA, Faubion WA. Sarmento OF, et al. Among authors: svingen pa. J Biol Chem. 2017 Jan 13;292(2):706-722. doi: 10.1074/jbc.M116.749663. Epub 2016 Dec 1. J Biol Chem. 2017. PMID: 27909059 Free PMC article.
Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation.
Bamidele AO, Svingen PA, Sagstetter MR, Sarmento OF, Gonzalez M, Braga Neto MB, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA Jr. Bamidele AO, et al. Among authors: svingen pa. Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):55-71. doi: 10.1016/j.jcmgh.2018.08.009. eCollection 2019. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30510991 Free PMC article.
BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease.
Gonzalez MM, Bamidele AO, Svingen PA, Sagstetter MR, Smyrk TC, Gaballa JM, Hamdan FH, Kosinsky RL, Gibbons HR, Sun Z, Ye Z, Nair A, Ramos GP, Braga Neto MB, Wixom AQ, Mathison AJ, Johnsen SA, Urrutia R, Faubion WA Jr. Gonzalez MM, et al. Among authors: svingen pa. J Clin Invest. 2021 Jun 15;131(12):e140755. doi: 10.1172/JCI140755. J Clin Invest. 2021. PMID: 34128475 Free PMC article.
The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival.
Rahman MK, Midtling EH, Svingen PA, Xiong Y, Bell MP, Tung J, Smyrk T, Egan LJ, Faubion WA Jr. Rahman MK, et al. Among authors: svingen pa. J Immunol. 2010 Jun 15;184(12):7247-56. doi: 10.4049/jimmunol.0901479. Epub 2010 May 7. J Immunol. 2010. PMID: 20483763 Free PMC article.
50 results