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Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide.
Swaminathan S, Birudukota S, Thakur MK, Parveen R, Kandan S, Juluri S, Shaik S, Anand NN, Burri RR, Kristam R, Hallur MS, Rajagopal S, Schreuder H, Langer T, Rudolph C, Ruf S, Dhakshinamoorthy S, Gosu R, Kannt A. Swaminathan S, et al. Biochem Biophys Res Commun. 2017 Sep 16;491(2):416-422. doi: 10.1016/j.bbrc.2017.07.087. Epub 2017 Jul 15. Biochem Biophys Res Commun. 2017. PMID: 28720493
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Kannt A, Rajagopal S, Kadnur SV, Suresh J, Bhamidipati RK, Swaminathan S, Hallur MS, Kristam R, Elvert R, Czech J, Pfenninger A, Rudolph C, Schreuder H, Chandrasekar DV, Mane VS, Birudukota S, Shaik S, Zope BR, Burri RR, Anand NN, Thakur MK, Singh M, Parveen R, Kandan S, Mullangi R, Yura T, Gosu R, Ruf S, Dhakshinamoorthy S. Kannt A, et al. Among authors: swaminathan s. Sci Rep. 2018 Feb 26;8(1):3660. doi: 10.1038/s41598-018-22081-7. Sci Rep. 2018. PMID: 29483571 Free PMC article.
Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Ruf S, Rajagopal S, Kadnur SV, Hallur MS, Rani S, Kristam R, Swaminathan S, Zope BR, Gondrala PK, Swamy I, Putta VPRK, Kandan S, Zech G, Schreuder H, Rudolph C, Elvert R, Czech J, Birudukota S, Siddiqui MA, Anand NN, Mane VS, Dittakavi S, Suresh J, Gosu R, Ramesh M, Yura T, Dhakshinamoorthy S, Kannt A. Ruf S, et al. Among authors: swaminathan s. Sci Rep. 2022 Sep 14;12(1):15440. doi: 10.1038/s41598-022-19634-2. Sci Rep. 2022. PMID: 36104373 Free PMC article.
The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
Lukacs C, Belunis C, Crowther R, Danho W, Gao L, Goggin B, Janson CA, Li S, Remiszewski S, Schutt A, Thakur MK, Singh SK, Swaminathan S, Pandey R, Tyagi R, Gosu R, Kamath AV, Kuglstatter A. Lukacs C, et al. Among authors: swaminathan s. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1717-25. doi: 10.1107/S0907444913016284. Epub 2013 Aug 15. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23999295 Free PMC article.
An Electronic Health Record-Integrated Application for Standardizing Care and Monitoring Patients With Autosomal Dominant Polycystic Kidney Disease Enrolled in a Tolvaptan Clinic: Design and Implementation Study.
Chedid M, Chebib FT, Dahlen E, Mueller T, Schnell T, Gay M, Hommos M, Swaminathan S, Garg A, Mao M, Amberg B, Balderes K, Johnson KF, Bishop A, Vaughn JK, Hogan M, Torres V, Chaudhry R, Zoghby Z. Chedid M, et al. Among authors: swaminathan s. JMIR Med Inform. 2024 May 1;12:e50164. doi: 10.2196/50164. JMIR Med Inform. 2024. PMID: 38717378 Free PMC article.
1,655 results