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Phytochemical profiling and bioactivity assessment of underutilized Symphytum species in comparison with Symphytum officinale.
Luca SV, Zengin G, Kulinowski Ł, Sinan KI, Skalicka-Woźniak K, Trifan A. Luca SV, et al. J Sci Food Agric. 2024 May;104(7):3971-3981. doi: 10.1002/jsfa.13279. Epub 2024 Jan 22. J Sci Food Agric. 2024. PMID: 38252561
BACKGROUND: Symphytum (comfrey) genus, particularly Symphytum officinale, has been empirically used in folk medicine mainly for its potent anti-inflammatory properties. In an attempt to shed light on the valorization of less known taxa, the current study eval …
BACKGROUND: Symphytum (comfrey) genus, particularly Symphytum officinale, has been empirically used in folk medicine ma …
Evaluation of the dietetic and therapeutic potential of a high molecular weight hydroxycinnamate-derived polymer from Symphytum asperum Lepech. Regarding its antioxidant, antilipoperoxidant, antiinflammatory, and cytotoxic properties.
Barthomeuf CM, Debiton E, Barbakadze VV, Kemertelidze EP. Barthomeuf CM, et al. J Agric Food Chem. 2001 Aug;49(8):3942-6. doi: 10.1021/jf010189d. J Agric Food Chem. 2001. PMID: 11513693
A water-soluble hydroxycinnamate-derived polymer (>1000 kDa) from Symphytum asperum Lepech. (Boraginaceae) strongly reduced the diphenylpicrylhydrazyl radical (IC(50) approximately 0.7 microg/mL) and inhibited the nonenzymatic lipid peroxidation of bovine brain e …
A water-soluble hydroxycinnamate-derived polymer (>1000 kDa) from Symphytum asperum Lepech. (Boraginaceae) strongly reduced …
Poly[3-(3,4-dihydroxyphenyl)glyceric acid], a new biologically active polymer from Symphytum asperum Lepech. and S. caucasicum Bieb. (Boraginaceae).
Barbakadze V, Kemertelidze E, Targamadze I, Mulkijanyan K, Shashkov AS, Usov AI. Barbakadze V, et al. Molecules. 2005 Sep 30;10(9):1135-44. doi: 10.3390/10091135. Molecules. 2005. PMID: 18007379 Free PMC article.
Two high-molecular water-soluble preparations with high anticomplementary, antioxidant, antilipoperoxidant and antiinflammatory activities were isolated from the roots of Symphytum asperum and S. caucasicum. Their main chemical constituent was found to be poly[oxy-1 …
Two high-molecular water-soluble preparations with high anticomplementary, antioxidant, antilipoperoxidant and antiinflammatory activities w …
[Development of technology for the substance of poly[3-(3,4-dihydroxyphenyl) glyceric acid] from Symphytum asperum].
Gokadze SI, Barbakadze VV, Gogilashvili LM, Amiranashvili LSh, Bakuridze AD. Gokadze SI, et al. Georgian Med News. 2013 May;(218):72-7. Georgian Med News. 2013. PMID: 23787512 Russian.
Comfrey (Symphytum L.) is used to treat bone fractures, tendon injuries, ulcer lesions of gastrointestinal tract. It promotes wound healing, accelerates exudates resorption in lungs and reduces joints' inflammation. In Georgian folk medicine, herbal remedies from …
Comfrey (Symphytum L.) is used to treat bone fractures, tendon injuries, ulcer lesions of gastrointestinal tract. It promotes …
Antimicrobial Activity of Catechol-Containing Biopolymer Poly[3-(3,4-dihydroxyphenyl)glyceric Acid] from Different Medicinal Plants of Boraginaceae Family.
Barbakadze V, Merlani M, Gogilashvili L, Amiranashvili L, Petrou A, Geronikaki A, Ćirić A, Glamočlija J, Soković M. Barbakadze V, et al. Antibiotics (Basel). 2023 Feb 1;12(2):285. doi: 10.3390/antibiotics12020285. Antibiotics (Basel). 2023. PMID: 36830198 Free PMC article.
This study reports the antimicrobial activities of the biopolymers poly[3-(3,4-dihydoxyphenyl)glyceric acid] (PDHPGA) and poly[2-methoxycarbonyl-3-(3,4-dihydroxyphenyl)oxirane] (PMDHPO), extracted from the six plants of Boraginaceae family: Symphytum asperum (SA), S …
This study reports the antimicrobial activities of the biopolymers poly[3-(3,4-dihydoxyphenyl)glyceric acid] (PDHPGA) and poly[2-methoxycarb …
[Novel biologically active polymer of 3-(3,4-dihydroxyphenyl)glyceric acid from two types of the comphrey Symphytum asperum and S. caucasicvum (Boraginoceae)].
Barbakadze VV, Kemertelidze EP, Targamadze IL, Shashkov AS, Usov AI. Barbakadze VV, et al. Bioorg Khim. 2002 Jul-Aug;28(4):362-6. doi: 10.1023/a:1019552110312. Bioorg Khim. 2002. PMID: 12197395 Russian.
Two high-molecular water-soluble preparations with high anticomplement and antioxidant activity were isolated from the roots of Symphytum asperum and S. caucasicum. Their main chemical constituent was found to be poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene] a …
Two high-molecular water-soluble preparations with high anticomplement and antioxidant activity were isolated from the roots of Symphytum …
Enzymatic Synthesis and Antimicrobial Activity of Oligomer Analogues of Medicinal Biopolymers from Comfrey and Other Species of the Boraginaceae Family.
Merlani M, Scheibel DM, Barbakadze V, Gogilashvili L, Amiranashvili L, Geronikaki A, Catania V, Schillaci D, Gallo G, Gitsov I. Merlani M, et al. Pharmaceutics. 2022 Jan 4;14(1):115. doi: 10.3390/pharmaceutics14010115. Pharmaceutics. 2022. PMID: 35057011 Free PMC article.
Antibacterial assessment of natural polyethers from different species of Boraginaceae family Symhytum asperum, S. caucasicum,S. grandiflorum, Anchusa italica, Cynoglossum officinale, and synthetic polymers, poly[2-methoxycarbonyl-3-(3,4-dimethoxyphenyl)oxirane (PMDMPO) and …
Antibacterial assessment of natural polyethers from different species of Boraginaceae family Symhytum asperum, S. caucasicum,S. grand …
11 results