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Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.
Pereira Tde A, Witek RP, Syn WK, Choi SS, Bradrick S, Karaca GF, Agboola KM, Jung Y, Omenetti A, Moylan CA, Yang L, Fernandez-Zapico ME, Jhaveri R, Shah VH, Pereira FE, Diehl AM. Pereira Tde A, et al. Among authors: syn wk. Lab Invest. 2010 Dec;90(12):1690-703. doi: 10.1038/labinvest.2010.147. Epub 2010 Aug 9. Lab Invest. 2010. PMID: 20697376 Free PMC article.
Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer.
Philips GM, Chan IS, Swiderska M, Schroder VT, Guy C, Karaca GF, Moylan C, Venkatraman T, Feuerlein S, Syn WK, Jung Y, Witek RP, Choi S, Michelotti GA, Rangwala F, Merkle E, Lascola C, Diehl AM. Philips GM, et al. Among authors: syn wk. PLoS One. 2011;6(9):e23943. doi: 10.1371/journal.pone.0023943. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912653 Free PMC article.
Role of stress-induced NKG2D ligands in liver diseases.
Kahraman A, Fingas CD, Syn WK, Gerken G, Canbay A. Kahraman A, et al. Among authors: syn wk. Liver Int. 2012 Mar;32(3):370-82. doi: 10.1111/j.1478-3231.2011.02608.x. Epub 2011 Jul 29. Liver Int. 2012. PMID: 22097967 Review.
Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma.
Chan IS, Guy CD, Chen Y, Lu J, Swiderska-Syn M, Michelotti GA, Karaca G, Xie G, Krüger L, Syn WK, Anderson BR, Pereira TA, Choi SS, Baldwin AS, Diehl AM. Chan IS, et al. Among authors: syn wk. Cancer Res. 2012 Dec 15;72(24):6344-50. doi: 10.1158/0008-5472.CAN-12-1068. Epub 2012 Oct 12. Cancer Res. 2012. PMID: 23066040 Free PMC article.
Fetuin-A mRNA expression is elevated in NASH compared with NAFL patients.
Kahraman A, Sowa JP, Schlattjan M, Sydor S, Pronadl M, Wree A, Beilfuss A, Kilicarslan A, Altinbaş A, Bechmann LP, Syn WK, Gerken G, Canbay A. Kahraman A, et al. Among authors: syn wk. Clin Sci (Lond). 2013 Oct;125(8):391-400. doi: 10.1042/CS20120542. Clin Sci (Lond). 2013. PMID: 23627434
141 results