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Insights from a Computational-Based Approach for Analyzing Autophagy Genes across Human Cancers.
Murillo Carrasco AG, Giovanini G, Ramos AF, Chammas R, Bustos SO. Murillo Carrasco AG, et al. Genes (Basel). 2023 Jul 28;14(8):1550. doi: 10.3390/genes14081550. Genes (Basel). 2023. PMID: 37628602 Free PMC article. Review.
Despite this, many questions remain to be elucidated and explored among the different tumors. Here, we used omics-based cancer datasets to identify autophagy genes as prognostic markers in cancer. ...In silico analysis allowed for identifying three genes (TBC1D12 …
Despite this, many questions remain to be elucidated and explored among the different tumors. Here, we used omics-based cancer datase …
Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection.
Baxter L, Gordon NS, Ott S, Wang J, Patel P, Goel A, Piechocki K, Silcock L, Sale C, Zeegers MP, Cheng KK, James ND; BladderPath trial management group; Bryan RT, Ward DG. Baxter L, et al. Sci Rep. 2023 Jan 19;13(1):1060. doi: 10.1038/s41598-023-27675-4. Sci Rep. 2023. PMID: 36658180 Free PMC article.
Mutations at specific hotspots in non-coding regions of ADGRG6, PLEKHS1, WDR74, TBC1D12 and LEPROTL1 frequently occur in bladder cancer (BC). These mutations could function as biomarkers for the non-invasive detection of BC but this remains largely unexplored. ...
Mutations at specific hotspots in non-coding regions of ADGRG6, PLEKHS1, WDR74, TBC1D12 and LEPROTL1 frequently occur in bladder c …
A study of gene expression by RNA-seq in patients with prostate cancer and in patients with Parkinson disease: an example of inverse comorbidity.
Pepe P, Vatrano S, Cannarella R, Calogero AE, Marchese G, Ravo M, Fraggetta F, Pepe L, Pennisi M, Romano C, Ferri R, Salemi M. Pepe P, et al. Mol Biol Rep. 2021 Nov;48(11):7627-7631. doi: 10.1007/s11033-021-06723-0. Epub 2021 Oct 10. Mol Biol Rep. 2021. PMID: 34628580
BACKGROUND: Prostate cancer (PCa) is one of the leading causes of death in Western countries. ...Several studies have indicated that the expression of target genes in patients with PD is inversely related to cancer development; this phenomenon has been named "invers …
BACKGROUND: Prostate cancer (PCa) is one of the leading causes of death in Western countries. ...Several studies have indicated that …
Identification of the BRAF V600E mutation in gastroenteropancreatic neuroendocrine tumors.
Park C, Ha SY, Kim ST, Kim HC, Heo JS, Park YS, Lauwers G, Lee J, Kim KM. Park C, et al. Oncotarget. 2016 Jan 26;7(4):4024-35. doi: 10.18632/oncotarget.6602. Oncotarget. 2016. PMID: 26684240 Free PMC article.
The mean numbers of somatic mutations in each case varied widely from 20 to 4682. Among 12 GEP-NETs, eight showed mutations of more than one cancer-related gene, including TP53, CNBD1, RB1, APC, BCOR, BRAF, CTNNB1, EGFR, EP300, ERBB3, KDM6A, KRAS, MGA, MLL3, PTEN, RASA1, S …
The mean numbers of somatic mutations in each case varied widely from 20 to 4682. Among 12 GEP-NETs, eight showed mutations of more than one …