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T-Box Transcription Factor 22 Is an Immune Microenvironment-Related Biomarker Associated With the BRAF V600E Mutation in Papillary Thyroid Carcinoma.
Dong X, Song J, Hu J, Zheng C, Zhang X, Liu H. Dong X, et al. Front Cell Dev Biol. 2020 Dec 17;8:590898. doi: 10.3389/fcell.2020.590898. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33392186 Free PMC article.
T-box transcription factor 22 (TBX22) is a phylogenetically conserved family member that has not been widely characterized in cancers. ...Functional enrichment analysis revealed that cancer-related pathways and immune progress were closely associated with …
T-box transcription factor 22 (TBX22) is a phylogenetically conserved family member that has not been widely characterized in canc
Distinct genetic alterations in colorectal cancer.
Ashktorab H, Schäffer AA, Daremipouran M, Smoot DT, Lee E, Brim H. Ashktorab H, et al. PLoS One. 2010 Jan 26;5(1):e8879. doi: 10.1371/journal.pone.0008879. PLoS One. 2010. PMID: 20126641 Free PMC article.
BACKGROUND: Colon cancer (CRC) development often includes chromosomal instability (CIN) leading to amplifications and deletions of large DNA segments. ...Some CAN genes were altered at high frequencies in AAs with EXOC4, EPHB6, GNAS, MLL3 and TBX22 as the most frequ …
BACKGROUND: Colon cancer (CRC) development often includes chromosomal instability (CIN) leading to amplifications and deletions of la …
The genetic factors contributing to the risk of cleft lip-cleft palate and their clinical utility.
Askarian S, Gholami M, Khalili-Tanha G, Tehrani NC, Joudi M, Khazaei M, Ferns GA, Hassanian SM, Avan A, Joodi M. Askarian S, et al. Oral Maxillofac Surg. 2023 Jun;27(2):177-186. doi: 10.1007/s10006-022-01052-3. Epub 2022 Apr 15. Oral Maxillofac Surg. 2023. PMID: 35426585 Review.
There is a growing body of data illustrating the association of several genes with risk of developing this malformation, including genetic defects in T-box transcription factor-22 (TBX22), interferon regulatory factor-6 (IRF6), and poliovirus receptor-like-1 (PVRL1), respo …
There is a growing body of data illustrating the association of several genes with risk of developing this malformation, including genetic d …
Microdeletion del(22)(q12.2) encompassing the facial development-associated gene, MN1 (meningioma 1) in a child with Pierre-Robin sequence (including cleft palate) and neurofibromatosis 2 (NF2): a case report and review of the literature.
Davidson TB, Sanchez-Lara PA, Randolph LM, Krieger MD, Wu SQ, Panigrahy A, Shimada H, Erdreich-Epstein A. Davidson TB, et al. BMC Med Genet. 2012 Mar 22;13:19. doi: 10.1186/1471-2350-13-19. BMC Med Genet. 2012. PMID: 22436304 Free PMC article. Review.
Additionally, Mn1 regulates maturation and function of calvarial osteoblasts and is an upstream regulator of Tbx22, a gene associated with murine and human cleft palate. This suggests that deletion of MN1 in the six patients we describe may be causally linked to their clef …
Additionally, Mn1 regulates maturation and function of calvarial osteoblasts and is an upstream regulator of Tbx22, a gene associated …
An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.
Brim H, Abu-Asab MS, Nouraie M, Salazar J, Deleo J, Razjouyan H, Mokarram P, Schaffer AA, Naghibhossaini F, Ashktorab H. Brim H, et al. PLoS One. 2014 Jan 27;9(1):e82185. doi: 10.1371/journal.pone.0082185. eCollection 2014. PLoS One. 2014. PMID: 24475022 Free PMC article.
BACKGROUND: Different DNA aberrations processes can cause colorectal cancer (CRC). Herein, we conducted a comprehensive molecular characterization of 27 CRCs from Iranian patients. ...The CGH data was compared to two established lists of 41 and 68 cancer genes, resp …
BACKGROUND: Different DNA aberrations processes can cause colorectal cancer (CRC). Herein, we conducted a comprehensive molecular cha …